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  1. ME/CFS Skeptic
    Post

    If ME/CFS research got £1 billion, what would stop it being wasted?

    Yes but even in this area it does not look impressive. The RECOVER study on ME/CFS post-covid did not include medical examinations so it was worse...
    Post by: ME/CFS Skeptic, Jan 24, 2025 in forum: General ME/CFS discussion
  2. ME/CFS Skeptic
    Post

    If ME/CFS research got £1 billion, what would stop it being wasted?

    Isn't that what happened in the US with the Long Covid money?
    Post by: ME/CFS Skeptic, Jan 24, 2025 in forum: General ME/CFS discussion
  3. ME/CFS Skeptic
    Post

    2025: The 2019/24 Cochrane Larun review Exercise Therapy for CFS - including IAG, campaign, petition, comments and articles

    Quote from the retraction watch article: Back in 2019, we made an overview of guidelines and policies that referred to the GET review here:...
    Post by: ME/CFS Skeptic, Jan 23, 2025 in forum: 2021 Cochrane Exercise Therapy Review
  4. ME/CFS Skeptic
    Post

    Cochrane Review: 'Exercise therapy for chronic fatigue syndrome', Larun et al. - New version October 2019 and new date December 2024

    Where did this funding come from? Was it a government grant that they lost or simply overall budget cuts?
    Post by: ME/CFS Skeptic, Jan 23, 2025 in forum: Psychosomatic research - ME/CFS and Long Covid
  5. ME/CFS Skeptic
    Post

    2025: The 2019/24 Cochrane Larun review Exercise Therapy for CFS - including IAG, campaign, petition, comments and articles

    Any articles on this because it seems like a strange decision.
    Post by: ME/CFS Skeptic, Jan 23, 2025 in forum: 2021 Cochrane Exercise Therapy Review
  6. ME/CFS Skeptic
    Post

    2025: The 2019/24 Cochrane Larun review Exercise Therapy for CFS - including IAG, campaign, petition, comments and articles

    Yes GRADE recommends downgrading for imprecision if the CI crosses the threshold of interest. Which is the case here.
    Post by: ME/CFS Skeptic, Jan 23, 2025 in forum: 2021 Cochrane Exercise Therapy Review
  7. ME/CFS Skeptic
    Post

    2025: The 2019/24 Cochrane Larun review Exercise Therapy for CFS - including IAG, campaign, petition, comments and articles

    I noticed that Lillebeth Larun has now responded to a comment:...
    Post by: ME/CFS Skeptic, Jan 22, 2025 in forum: 2021 Cochrane Exercise Therapy Review
  8. ME/CFS Skeptic
    Post

    Should we change our name: 'ME/CFS Skeptic'?

    Thanks for all the comments and suggestions. We have just posted the following poll on social media based on 3 options that we like the best thus...
    Post by: ME/CFS Skeptic, Jan 21, 2025 in forum: General ME/CFS news
  9. ME/CFS Skeptic
    Post

    Misdiagnosis of an underlying medical condition as Conversion Disorder/Functional Neurological Disorder (CD/FND), 2020, van der Feltz-Cornelis et al

    https://eprints.whiterose.ac.uk/164981/1/20200428ConversiondisordermisdagnosisGHPaccepted_combined_1_.pdf
    Post by: ME/CFS Skeptic, Jan 16, 2025 in forum: Other psychosomatic news and research
  10. ME/CFS Skeptic
    Post

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    Thanks. The data is in .raw filetype and have some trouble converting it to something like CSV or Excel. Anyone who has more experience in this?
    Post by: ME/CFS Skeptic, Jan 16, 2025 in forum: ME/CFS research
  11. ME/CFS Skeptic
    Post

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    This study is listed on MapME/CFS but it doesn't include the raw data from what I can see, only summary statistics of their analyses and modelling.
    Post by: ME/CFS Skeptic, Jan 15, 2025 in forum: ME/CFS research
  12. ME/CFS Skeptic
    Post

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    Just posting the main results here: The Japanese used next-generation sequencing (NGS) and got the following results: [ATTACH] They also found...
    Post by: ME/CFS Skeptic, Jan 15, 2025 in forum: ME/CFS research
  13. ME/CFS Skeptic
    Post

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    Any ideas at what this may point to? If it is not specific antigen driven expansion, what else might be causing this? And why would B-cell...
    Post by: ME/CFS Skeptic, Jan 15, 2025 in forum: ME/CFS research
  14. ME/CFS Skeptic
    Post

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    Wrote a short section about this in our 2021 review of ME/CFS studies:
    Post by: ME/CFS Skeptic, Jan 15, 2025 in forum: ME/CFS research
  15. ME/CFS Skeptic
    Post

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    Thanks, the two studies these refer to are I believe: 2020 Lipkin study: Plasma proteomic profiling suggests an association between antigen...
    Post by: ME/CFS Skeptic, Jan 15, 2025 in forum: ME/CFS research
  16. ME/CFS Skeptic
    Post

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    Looks interesting. The first author is Audrey Ryback who is also trying to replicate the 'something in the blood' theory, as explained by Simon...
    Post by: ME/CFS Skeptic, Jan 15, 2025 in forum: ME/CFS research
  17. ME/CFS Skeptic
    Post

    Review Interventions for the management of long covid post-covid condition: living systematic review, 2024, Zeraatkar, Flottorp, Garner, Busse+

    More than a month later and there is still no peer review or reply from the authors to the comments made.
    Post by: ME/CFS Skeptic, Jan 15, 2025 in forum: Psychosomatic research - ME/CFS and Long Covid
  18. ME/CFS Skeptic
    Post

    Should we change our name: 'ME/CFS Skeptic'?

    Thanks for the suggestions. It seems that misuse of the term skeptic has become so common (i.e. as in climate skeptics) that a correct use of the...
    Post by: ME/CFS Skeptic, Jan 14, 2025 in forum: General ME/CFS news
  19. ME/CFS Skeptic
    Post

    Incidence and Prevalence of Post-COVID-19 Myalgic Encephalomyelitis: A Report from the Observational RECOVER-Adult Study, 2024, Vernon +

    Later in the text they write: So that suggests that one ME/CFS symptom is enough to meet the ME/CFS-like definition. What they call ME/CFS...
    Post by: ME/CFS Skeptic, Jan 14, 2025 in forum: ME/CFS research
  20. ME/CFS Skeptic
    Post

    Incidence and Prevalence of Post-COVID-19 Myalgic Encephalomyelitis: A Report from the Observational RECOVER-Adult Study, 2024, Vernon +

    Bit sad that they got more than 1 billion in funding and this is the best they could do...
    Post by: ME/CFS Skeptic, Jan 13, 2025 in forum: ME/CFS research
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