Just found this thread quite informative/refreshed my memory....
Are any of these findings viable drug targets? I would have thought it was far too early for anything like that but very happy to be wrong....
So from what I can understand, they are claiming this is a replication of an earlier study, which seems like a big deal. And again Precision Life...
https://www.medrxiv.org/content/10.1101/2025.02.04.25320937v1.full.pdf+html New Precision Life preprint that was shared by Chris Ponting in...
Surely that is a model of the itaconate shunt, which is obviously a valid theory but has never been proven in ME, so even if the model is accurate...
That's why I was fascinated by the muscle on a chip abstract that was doing the rounds a little while back. Similar thing but with lab grown...
What do we think this means in the context of the nanoneedle study? Is this paper outlining a need in research ahead of publication, or does this...
There was also the IgG mouse model studies from den Dunnen and Putrino/Iwasaki where they gave the mice serum or plasma (my scientific knowledge...
It could be worth pursuing then, even if tricky. Hard to get funding without more evidence though I'd imagine. Interesting, can you say more...
So a GWAS wouldn't pick it up if it was due to disordered expression rather than defect? A fascinating and horrifying thought. If there are no...
All of these findings lately are making me think about the fact that I have had 'blood sugar crashes' since my late teens, the time when I...
A nonentity of an answer that embodies the governments willfull ignorance over the realities of living with ME. The state supported me in my...
This is the team that is doing the nanoneedle replication attempt iirc.
'Simmaron has already found 130 age and gender-matched healthy controls over the past year, but they are not including a placebo arm in this trial...
This stood out to me...
I stumbled across this earlier which looks interesting although it was serum and CSF. Also there was that muscle on a chip abstract and the two...
Whoever made the decision to print that last letter has blood on their hands. The Guardian editorial team cannot keep both sidesing this. People...
I suspected I had 'Cfs' for years but the NHS page was terrible and didn't mention PEM, and doctors were dismissive. I assumed that it just meant...
I agree about trying to replicate complement H and other complement findings, and hv3-30. I just want to say that I think severe patients should...
I just want to chime in and say that the left and liberal academia in humanities really likes ideas of psychosomatic illness and the like. I wrote...
Separate names with a comma.
