"In neurodegenerative diseases, microglia switch to an activated state, which results in excessive secretion of pro-inflammatory factors. Our work...
For me, antihistamines give me more mental and physical energy. I can sit and play a game of cards without being cranky and exhausted while...
I use Reactine (H1) and Pepcid (H2). Pepcid is about the only OTC H2 available in Canada. I've also found Benadryl has a good effect, though it...
I've had really good success with the mast cell protocol of H1/H2 antihistamines and reducing histamine containing foods. For years I've had a...
I did a two day exercise test at a facility that usually tests athletes. When I asked if there was anything unusual in the tests the lady said...
https://www.nature.com/articles/s41564-023-01349-3 The development of persistent cellular reservoirs of latent human immunodeficiency virus (HIV)...
In 2013/2014 the authors started a patent (withdrawn) for NO treatment of ME/CFS Nitric oxide donor for the treatment of chronic fatigue syndrome
One day I was standing at the grocery store checkout with a red cabbage on the scale. It didn't have a number sticker so I was trying to enter the...
"It has been shown that innate immune responses can adopt adaptive properties such as memory. Whether T cells utilize innate immune signaling...
Last year at age 63 I discovered I was autistic. I score at the top end of the standard tests. The closest I could get to confirmation was a...
In general, the H1 inhibitors are found as over the counter allergy medication. The H2 inhibitors are the ones that can be found in over the...
The best web resource I've found is https://www.mastattack.org/2014/10/mcas-treatment/ I've pointed to the treatment page but the rest of the...
Moved posts from Diagnosis of mast cell activation syndrome: a global “consensus-2”, 2020, Afrin et al Warning: anecdotal I've been mostly bed...
When I'm lying down I compose email responses in my head, often recomposing them until I get them right. As soon as I stand up and walk into the...
"Herpes simplex virus (HSV) establishes latency in ganglionic neurons of the peripheral nervous system, from which it can reactivate, causing...
Abstract The outbreak of SARS-CoV-2 infection has enormously impacted our lives. Clinical evidence has implicated the emergence of cytokine...
Abstract Numerous mitochondrial constituents and metabolic products can function as damage-associated molecular patterns (DAMPs) and promote...
"Successful elimination of bacteria in phagocytes occurs in the phago-lysosomal system, but also depends on mitochondrial pathways. Yet, how these...
"This review provides a brief history of how our knowledge of endothelial function has advanced and now recognize that the endothelium produces a...
"The findings of the present investigation provide evidence that aging-related endothelial dysfunction and arterial stiffening are significantly...
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