https://news.stanford.edu/2020/07/21/researchers-develop-portable-ammonia-detector/ Stanford researchers develop a portable blood ammonia detector...
https://grantome.com/grant/NIH/R01-DK082528-01S1 Regulation of Energy Metabolism by PDP1 and PDP2
I worked out that theoretically my NAGS gene will be underactive along with a gene for pyruvate Maybe low pyruvate makes it harder to detox ammonia
Genetically I have a distant connection to NAGS deficiency I’m hoping it maybe partial NAGS with treatment but it maybe a long shot It’s treatment...
I ended up at the liver potentially being my central cause as well,specifically under active enzyme of the urea cycle possibly resulting in...
If you can’t detox ammonia via the liver the brain and muscle can be utilised(2:20) and exercise increases the problem 3 fold (10:40) [MEDIA]...
I’m wondering if I may have something like partial NAGS deficiency (slc13a3) and found this on very rare urea cycle disorders...
Pyruvate in general has been mentioned before in M.E Fluge and mella Ron Davis pyruvate normalises blood and so does copaxone And dr bhupesh...
One of the hallmarks was that it was a cluster outbreak very few mecfs are part of a cluster outbreak these days Could it of been a coronavirus...
Interesting study,I wonder if there are any updates
[MEDIA]...
https://pubmed.ncbi.nlm.nih.gov/32500504/ SARS-Coronavirus-2 Nsp13 Possesses NTPase and RNA Helicase Activities That Can Be Inhibited by Bismuth Salts
If you have genes related to dementia risk (APOE)ect,are you more likely to develop M.E And severe COVID as a few papers have suggested....
[MEDIA]
https://www.jns-journal.com/article/S0022-510X(20)30282-3/fulltext COVID-19-associated delayed posthypoxic necrotizing leukoencephalopathy
COVID-19 –associated Diffuse Leukoencephalopathy and Microhemorrhages https://pubs.rsna.org/doi/10.1148/radiol.2020202040
https://pubs.rsna.org/doi/10.1148/radiol.2020202040 COVID-19 –associated Diffuse Leukoencephalopathy and Microhemorrhages
I saw rituximab described as the only approved anti EBV therapy I wonder if assessed on a case by case basis if it might be useful to me
PITX2 activates PDP2 so theoretically I’ll have low pyruvate dehydrogenase as I have a point mutation in PITX2...
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