Maybe the right time is to measure every day for a week while the patient is doing a little too much. Not enough to cause a serious crash but...
A study by Morten and his Polish collaborators found a decrease in central energy metabolism in patients with ME/CFS when comparing pre and post...
Is this saying that oxygen-dependent energy production decreased?
I've been going swimming almost every day lately and there is a trend of finding it increasingly difficult over time. I keep having to reduce the...
I believe that something like LP has a high risk of long term harm because it attempts to persuade patients to believe in something that is not...
As far as I know, there's still no evidence somatization is actually a thing. They can't even define it clearly enough to allow falsification of...
@DMissa are you interested in hearing some ideas on how to investigate PEM and ME/CFS?
They defined it as tendency to avoid unwanted experiences.
Something like heat shock proteins being dysregulated might explain the poor stress and exertion tolerance of patients (they don't just protect...
Not liking the positive spin in the abstract. The questionnaire results don't look impressive and are uninterpretable due to lack of controls. I...
Illness doesn't begin at diagnosis. It's likely that all these people are already sick with whatever illness they have, even if it takes another...
HSF2 is required to maintain cell-cell adhesion HSF2 deficiency leads to downregulation of cadherin superfamily genes Impaired cell-cell adhesion...
Blog by a person who tracks her health data over time. [MEDIA] Observations Summary: Fluctuations in temperature, resting heart rate, inverted...
Hanson et al did not report which type of cadherin was elevated in ME/CFS, if any. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931008/ If one...
Adhesion molecules are cell surface proteins that mediate the interaction between cells, or between cells and the extracellular matrix (ECM)....
Something that has also happened to me is eating a lighter dinner than usual, and the next morning going out for a walk after the usual breakfeast...
When reading papers like this, I always have to think back to when I was getting therapy for "school refusal" (actually crippling fatigue, but...
A bit more information on what the WAVE3 gene does in the cell besides having something to do with mitochondria. It's part of a protein family...
Increased expression of this protein seems hard to interpret because it's involved in so many different things. But that the NIH is doing a...
My understanding is that the link to mitochondria is autophagy (degradation of damaged cellular components) and maybe also organization of the...
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