I know this sounds hopelessly idealistic (or just plain wrong) but a business case is supposed to inform and ask for (informed) consent. Since...
Thanks for the laugh - if only it were actionable ---
Reminds me of Paul Garner's Newsnight appearance were he assured us that he was ill and cured himself with the power of positive thought ---- if...
An unregulated charity which has a very poor record. I've copied an extract from my previous correspondence with NICE*. If NICE look at the...
Too realistic--- Unfortunately, despite the fancy words in the business case, re aligning Cochrane reviews with the needs of the system (NICE's...
Presumably if you use an unblinded study and subjective outcome criteria then you can get a positive result --- "Outcome measures Experiences,...
Moved post I've had a brief look at the business case. Comments from others on this forum that the "logic" was saving money i.e. through avoiding...
Thanks Michiel. @Caroline Struthers Michiel has posted the first response from NICE.
Copied post I submitted a request for: "The latest full business case for the NICE Cochrane collaborative agreement*. If not the same document,...
Perhaps the involvement of e.g. dopamine, serotonin, --- something neurological --- would be indicated by a GWAS study? Yes, it seems to be...
OK pretty much everyone on this site agrees that unblinded studies with subjective outcome criteria=useless crap (or worse) The question seems to...
I noticed an appraisal of the PACE trial which highlighted that there was no increase in (participants) hours worked, participation in education...
Unfortunately I could go with that abbreviated quote. I'm hoping that the GWAS study [Chris Ponting's] will help to focus biomarker studies and...
When do you anticipate sampling to start (saliva in tubes)?
Almost becoming a standard reply from me but the GWAS study (Chris Ponting - sampling starting in May) might provide a way to test hypothesis like...
This one's been kicking around for years [suramin as a treatment for ME/CFS*]; possibly Chris Ponting's GWAS study might provide an indication re...
From this it appears that NICE is doing what it should be i.e. evaluating the evidence. It's difficult to see how NICE could maintain those...
That grates given the amount of time and effort @Caroline Struthers has spent trying to get Cochrane to remove redundant reviews. I think...
I think @Jonathan Edwards is key i.e. The business case (hopefully released under FOI) should tease out these issues but I kind of expect the...
Yea I think there were some weasel words in NICEs reply i.e. assurances that NICE would review the evidence independently (of Cochrane) in...
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