Reminds me of this study: " The expression signature of very long non-coding RNA inmyalgic encephalomyelitis/chronic fatigue syndrome Chin‑An...
I think it may help to consider what the actimetry reading are for "purpose". E.g. the a PACE type study could probably be evaluated using fairly...
There's a thread somewhere, on this site, relating to a study comparing a "time upright" monitoring device versus questionnaires --- so perhaps...
I created a new thread here re Actimetry: https://www.s4me.info/threads/actimetry-studies.20638/
Hi, there have been some suggestions that an Actimetry study would be useful in ME/CFS; perhaps we could use this thread to discuss.
Yes, an actimetry study might e.g. look at off the shelf equipment [you mentioned fitbit] and more specialised equipment - there's a review, on...
Fluge and Mella used actimetry in the rituximab trial. I assume that those reluctant to use actimetry may be running studies on a very limited...
You seem to have set out a very good suggestion i.e. respond to the request, for ideas for future research areas, by outlining a study on the use...
Well done to all involved particularly @Andy In terms of suggestions @Jonathan Edwards has highlighted that he participated in an MRC group...
I wonder if Aptamers are a way of determining intracellular tryptophan concentrations - thereby testing whether intracellular levels are high...
I think the key thing, as @Michiel Tack has indicated, is to identify the role of IDO2 via a larger study e.g. Chris Ponting's GWAS study. The...
I think the identification of IDO2 is well documented i.e. Robert Phair looked carefully at a small number of genomes* and identified that all had...
Perhaps one for @Simon M. Would Chris Ponting's GWAS study establish whether the mutation of IDO2 you carry is relevant in terms of ME/CFS? E.g....
Bhupesh mentions a publication in Nature last year and a technique - slum seq ? Anyone know what this is? We published a paper in [the journal]...
Not directly relevant but Fluge and Mella published a paper suggesting impaired PDH - basically anything that needed to go through pyruvate was...
Yes - and if there is no evidence of anemia then you'd need to demonstrate that something else is sacrificed first like ---?
I need to re-read this. I agree with what you are saying e.g. I work in policy and the approach is often to set out the great things our...
Just to agree with you - a relative, who was a psysio, told me that they had to contact Doctors regularly - why did you refer patient X what is...
I was wondering if this undermines the concept of having confidence in peer reviewed science but then I realised it wasn't a peer reviewed...
I recall some comments by @Snow Leopard basically cortisol studies always find something. If I recall correctly the levels fluctuate naturally...
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