Does lower body negative pressure have the same physiological effect that being upright does?
That's the million dollar question if this is actually happening. As far as I am aware a few possibilities are: reduced cerebral blood flow, some...
The study itself showed that these psychiatric diagnosis had no impact on the measured parameters. What is more interesting to me are the...
It is also very hit-and-miss for me. Several times I have drank a coffee and spent the next twelve hours throwing up with terrible headaches....
Yeah that's about right from what I remember. I gave my samples about a year ago when I was still living in NYC. I'm surprised a preprint hasn't...
There are these two studies that I have recently found....
They state that: "Considering all these results together, it can be stated that there are widespread metabolic changes in many brain regions...
That is a good point. For me episodes of PEM have always been on the shorter side, but there are certainly those where PEM lasts longer then...
Jarred Younger presented some preliminary unpublished lactate data during the ME/CFS Research Roadmap series. It seemed to have a similar...
I'm curious where the issue with this logic is: Any theory of ME/CFS should explain why PEM from cognitive exertion occurs. At the most basic...
Yup exactly, sounds like I experience the disease in a similar way to you. If this were the case there is also likely to be multiple different...
Thanks, seems like a good list. You'd think these hypothesis wouldn't be that hard to test, I guess it just takes money, time and some rigorous...
Interesting. What are the alternative hypothesis for blood pooling in the extremities in POTS again? I know SFN is a potential cause but is there...
Thanks for posting this SNT. I do think a process like this could explain why cognitive overexertion would produce PEM. If the exertion produces...
I wanted to know if other pw ME/CFS experience any sort of paresthesia and what the possible causes are. I have had tingling and...
[ATTACH] Summary graph illustrating the vicious cycle linking research funding from vested interests, poor science, and limited accountability
The purpose isn't to ban anything, the purpose is to discover the truth and help improve the lives of patients. If psychological research were...
I submitted this comment: Funding for Researchers working on the Biological Basis of ME/CFS The NIH needs to make it clear, that only researchers...
I think it's more complicated to accurately measure it than what's commonly done. My understanding is typically the velocity of the blood is...
Compare this to the NIH study. In controls, the NIH that found 3/17 (17.6%) had OH and 7/17 (41%) had symptoms. The methodology might have been...
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