Does anyone have any thoughts on why none of the participants had pots? Is this a selection problem or are pots and ME just unrelated?? I really...
Certainly a confusing and wandering paper. My take away from reading for the first time is that there is some central issue but the authors...
Slightly off topic but I often think about how many other processes in the body could easily be thought of as functional if we had limited...
My problem with FND is when doctors and institutions claim that there is no physical or biological cause. The Mayo clinic's website states...
I have never understood the software v hardware analogy. Do they think software is some magical entity that has no physical basis? Software is...
One of the studies I am more excited to see results from!
Yes I worded that incorrectly, I think the decline on a 2-day CPET is likely to be associated with PEM in people with ME. However, I'm not...
I think we can be fairly certain that Vo2 max and other CPET measures are not analogous to PEM. If a healthy control experiences a reduction in...
So ironic that he recommends something which he claims jury is still out on... Perhaps that shows he hasn't in-fact comprehensively looked at...
"And now the brain goes into overdrive and starts over-interpreting even quite innocent stress and activates the pain" I've seen this kind of...
I will add that that study used a PET radiotracer that was developed in the 1980s and isn't as specific as the second generation ones that have...
Perhaps the act of death has a large impact on glial cells such that autopsies mightn't be the best way to study them. Apparently we can see large...
I really appreciate you pointing it out, it is my misguided assumption that the researchers would have a good understanding of the basics but I...
We are only now starting to gain the tools that are sensitive enough to know what the pathology of less overtly severe clinical symptoms are....
This has always been bizarre to me. When I first got sick I had a Vo2 max in the mid to high 70s (as a lightweight rower). Now that I have ME and...
The authors say "The ear lobe, which is devoid of vagal innervation, was chosen as the site of stimulation in the sham group. Patients were...
I'm not sure if this answers the question but I did find this in a review paper titled "The semantics of microglia activation: neuroinflammation,...
That is one of the things I find compelling about this theory. It offers an explanation why a number of seemly different unconnected triggers...
I don't know if I have missed something but it seems like there is much literature that certain viral infections can cause glial activation. I...
This makes sense in some cases but surely it is possible to have changes in the brain that do not result in clearly apparent issues like...
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