[ATTACH] In this figure panel they report on one of the top 2 significant metabolites associated with the difference between the first and second...
I wanted to make a post about this paper I think it's quite interesting. I like that by having a 4 time points and a longitudinal, paired design...
I love this! I was having a look through this data anyway and a resource like this would make it so much easier! It would be great (if and when...
It's interesting to see strong positive agreement about gamma-glutamylated amino acids (glutamate, lysine, tryptophan etc) in @Murph 's...
This is cool I have a lot of thoughts about this. First thing is Hoel 2021 use serum and Germain 2018 use plasma. The metabolomes of serum and...
Great article! George Monbiot is a very good ally
Thanks for this analysis Murph! Are these metabolites here significantly different in Baraniuk 2021? I had a quick skim but in the body of the...
I noticed that in the NIH paper some of the p values they report for their metabolites are higher than their adjusted p values. This doesn't make...
Urea cycle: Carbamoyl phosphate synthesis is the rate limiting step of the urea cycle, it's formed from the combination of ammonia and...
Oh yeah very good point. I haven't gone into that myself but if @LarsSG is right about this that's reassuring. To me it looks like maybe three...
[ATTACH] Spermidine is the second most significant hit in the NIH intramural study's metabolomic data, as well as other polyamine related...
Viewing the whole thing as a heatmap might be easier: [ATTACH]
Despite the small n=18 sample size and weird issues with categorization of severe ME I really like this paper. I like that by looking at the...
I read the first line and was thinking 'how bad could it be?' I wasn't expecting something that sounds so much like an aphrodisiac.
Another thought about this paper. So far every ME metabolomics paper I've seen doesn't have a disease control. I'm very keen to see that because...
Had a look in hanson urine study and it is lower relative to controls (0.7 of controls) but not significant p~0.3. Armstrong has also done some...
Biology This sounds interesting. It's interesting that all the reductions in membrane lipids they find are unsaturated (containing double bonds...
I'm revisiting some metabolomics papers and thought I'd share some thoughts about this one. I think it's potentially quite interesting. It's got...
The trend if anything looks to me like the fewer sessions you had the better your chances of improvement - for both activity management and GET.
[ATTACH] I just added a red line to this plot to make it easier to visualise (for me at least). If a dot is above the line they improved if it's...
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