So much agree from me on this comment! Absolutely an individual outcome in a context has its own degree of bias - and it's higher if it's...
I wish your first point was true! There are many other potential sources of bias - what a particular practitioner (or more) did that deviated from...
...which would count as a value from the trial (that it raised questions about other evidence for you, I mean). It provided data on adverse...
I'd said I would do this, but when I re-read this carefully, I don't think it's that simple. Even when trials are blinded, and even when the...
I don't believe I suggested that. Quite early on, I said I had trouble with the statement as it stood, and explained why people would disagree...
Apologies that my answer won't cover everything you mean. Sometimes, pain is a pivotal issue - when 2 options are roughly equal in all other known...
Thank you - that's nice, and I appreciate it! Oh yes, you can definitely count on me engaging robustly with Cochrane and others, and not being...
Thanks - that's nice! Not my first rodeo - and there's Twitter, which is a whole other level, and I do that. I never would have agreed to lead the...
OK, but can't do it right now - have to work.
I didn't think of that word as emotive, but happy to replace with another and won't keep using it. Global? All-encompassing? I totally agree that...
Unfortunately, Cochrane quality control of what it publishes even in Cochrane reviews isn't all it needs to be. I don't think it's necessarily...
The thing I've been debating is partly whether subjective outcomes in an unblinded treatment trial can ever justifiably be a primary endpoint, but...
However, I did just prove that I didn't have an epidural "...the trial might still have some value...I don't think anyone is suggesting...
Well, that'll teach me to use an obstetrics example without getting up-to-date on it first - in terms of whether you could have the epidural early...
I'm glad you're finding it helpful - thanks! And I'll check that out - thanks! Epidurals are done late in labor for a variety of reasons, so...
Somewhat similar, just more complicated. (That could be my answer to everything, eh?, "it's complicated"!)
I've replied elsewhere on the subject of trials being collections of data of unequal quality, so I won't reiterate that I don't think a problem in...
I agree with you in terms of being concerned with how some are approaching priority-setting, and that it could lead to a drift towards the...
Yeah, that's a really good point - but there's a lot of diversity opinion about individual trials, and not every review for example only includes...
Dismissing the trial as valueless is the problem: for example, why would the fact that women were asked to rate their own pain mean the data on...
Separate names with a comma.