Another reason to reject being very generous with claims of treatment efficacy is that patients are expected and sometimes pressured by society to...
One of the concerns is precisely the proliferation of studies that exploit the lack of reliability of subjective outcomes in an unblinded context...
I agree with him that an effective treatment can give us clues about causative factors. An ineffective treatment also does. The PACE trial...
What kind of problems can dysfunction of the innate immune system produce?
It could be a valid explanation for a subset. Hopefully Prusty can keep a cool head and not let attention from patients trigger excessive confidence.
[MEDIA] @Jonathan Edwards what do you think about his idea of innate immune system dysfunction?
Patients with devastating illnesses tend to have difficulties remaining objective when evaluating a treatment because they so desperately want it...
I meant that it's not a problem of the GP lacking good bedside manner. Some might do because they are frustrated, just like the patients. You're...
I thought about what kind of review of exercise therapy for ME/CFS would be appropriate. One with roughly the following content: A conclusion...
People don't trust their GP because their GP is told a lot of false/dubious things about ME/CFS or MUS, leading to immediate alienation, repeated...
I have some issues with describing urinary incontinence as subjective outcome. It think it's an objective outcome. It might be reported in a...
If mental health research was held to the same standard as the rest of medicine, large portions of it would simply collapse (and maybe that would...
At the risk of distracting with CCI, I just read on Twitter that in Italy, a doctor claimed multiple sclerosis was caused by a problem in the neck...
The gay conversion therapists probably said similar things. "We just want to help and there are these horrible militant activists staging protests...
Contains no details whatsover, but makes some bold claims. Best not to expect anything from this group.
My attempt to better explain how I see the lack of blinding + subjective outcomes problem. Lack of blinding makes subjective outcomes unreliable....
You mention trauma as cause of MUS. Is that really what they believe? They don't mention that in their explanations I believe. If so then their...
I've heard this kind of story many times now. It goes roughly like this: young person in school gets mono/flu-like illness, begins to struggle, is...
The thinking seems to be that it is okay to do open-label clinical trials with subjective outcomes if there is no objective marker of disease...
In a sense, their work is a test of whether the avoidance behaviour (of more than low activity levels) in ME/CFS can be unlearned or not. It can't...
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