I am quite sure that the patients are leading. DecodeME came about largely through the efforts of a member here and is co-run by a member. The...
Interesting. My thought would be that getting a bispecific or trispecific CAR-T to work using antigen specific ligands could require a whole...
OK, but my main contribution to medical science has been the deduction that for autoimmune disease there is no 'culprit' after all, just complex...
The criticism of the psychological interpretation is good but we need to be critical of the mix of data and interpretation in the immunology just...
If the larger discussion is more biology, fine. But as Trish points out vanElzakker has friends in persistent virus money gathering. And as...
I was at Grand Rounds at UCL yesterday. We talked about CAR-T for scleroderma. Everything is looking rather encouraging partly because Car-T may...
Sure, I may not have made that clear. We know that rituximab produces a rapid fall in some autoantibodies and not others. That suggests that...
Seems a bit like collecting non-fungible tokens. The more non-existent biopsychosocial diagnoses and corresponding unproven therapies you collect...
Wouldn't a pragmatic perspective be like ours - the samples are so small and the findings so marginal that nothing very much can be concluded?...
I had a look at the paper again. The B cell findings are unremarkable and we have similar studies from the past that showed nothing much. An...
It might be helpful if the document pointed out that NICE decided GET didn't even work, let alone the worries about harm!
Was there any evidence of antigenic stimulation? A few stray T cells possibly but T cells get activated by things other than antigens. Brain...
I don't see these results as leading to anything new. The studies on T and B cells are not significant with such a tiny sample. T cell...
This is an important point. At the Round Table it was made very clear that GET was not recommended because the evidence was inadequate to show...
That seems a good summary of the problem @EndME. I wonder if there is deeper confusion still. The title of paper is 'Measure of Autonomic...
Copied post This is nonsense but as a necessary upbeat take on a very costly study that was supposed to be groundbreaking it is excusable, and...
This is nonsense but as a necessary upbeat take on a very costly study that was supposed to be groundbreaking it is excusable, and at least a good...
In other words, from the outside world this looks like a non event. I think the coverage actually reflects that, in that it is all 'today's little...
I was approached by journalists saying 'This looks like a damp squib that the science community is going to forget. But maybe an opportunity to...
I think those just show how dependent rates are likely to be on recruitment routes, @Sid. Maybe blood donors aren't allowed to give blood if they...
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