My impression of 3e is that PWME have acquired a good sense of their fatiguability whereas healthy controls haven't a clue and are all over the...
"Some infectious diseases and cancers have been associated with the development of antinuclear antibodies, as have certain drugs." Certain drugs,...
If his agenda was to show that effort choice was down in the presence of a healthy body he would have found it convenient to note that the p value...
As far as I know positive ANA is not likely to be related to recent viral infection or viral persistence, certainly not speckled. The problem...
I doubt there is much new. Fiona Powrie used to talk about this stuff at meetings I presented at about 15 years ago. If you take away T regs in...
Yes, the usual garbling. Not even exhaustion after all? As far as I know T regs have little or nothing to do with most autoimmunity and of course...
The sample is too small to tell if they found anything in fact. And if they did it seems to me more like an 'odd smell' rather than smoke. It...
Except that this study provides no basis for such trials. It shows no evidence for a need to 'clear antigen' even if checkpoint inhibitors were...
I have emailed Charles Shepherd.
I have only just seen this. A think it warrants an apology. Hopefully it was said in the heat of the moment.
I am thinking more in the terms bobbler is raising, that the measurements of effort choices in this NIH study aren't being taken in a context that...
I am reminded (by @bobbler and @Hutan's efforts) of the debate about incompatibility of General Relativity and Quantum Theory. This worries a lot...
From past experience @bobbler I suspect you are missing nothing. My brain is too old and my attention span too short to help but I suspect there...
I do not doubt `Cochrane's ability to bias their output, but my point was that in this particular case I don't see it as being obvious how these...
Something that struck me is that if this 'toolkit' is just for ongoing clinical monitoring then these aren't 'outcome' measures. They are...
OK, but what is the clinical assessment for? If we have no treatments that we know depend on such assessments I would have thought it more useful...
Dilutions would make interpretation a bit easier but it remains the case that at some cut off the positive rate was five times higher in patients....
Yes, that would be a classic type 2 error. So the claim that the autoantibodies were not elevated was bogus in fact. Inasmuch as it could be...
They certainly leave the door more than ajar but I cannot see this as being cited in a Cochrane review in a conclusion that says 'Even if the...
I find this very strange. As far as I know nobody as found any evidence of residual antigen and the weight of evidence in post-infective syndromes...
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