I doubt it. My main concern is that PWME are bound to be in a different autonomic state because they are the ones being tested for an illness -...
I am not sure that propping up ideology can have any impact on a review of evidence for efficacy of treatments. And in as much as this study says...
I am sure that happens, but an increase in symptoms and increasing debility are seen in almost any condition limiting exertion capacity. It occurs...
Indeed they have. Every study is different but the DecodeME study put a lot of effort into getting the criteria, numbers and recruitment right for...
Except that they then say it might be jolly good to add them in to the immune treatments in a nice personalised mixture dreamt up by the 'expert'...
Any disease of unknown cause that fails to respond to rituximab might do so because it is driven by long lived plasma cells. At present I think...
No that's the 64 MILLION dollar question.
Good to see this from Wust: "The pathology of reduced exercise capacity is different from PEM" I get the impression that he is someone who...
Yes I am getting that now. I am so glad S4ME members are such Trojan data readers. I give up when I cannot see what a result is supposed to mean....
The sceptical response would be that we had pretty much as good results as this in our first lupus study in 2000 with rituximab. But I am very...
Don't know. It is a bit surprising to me but may be within normal expectations.
Agreed. It seems they could be picked if they fulfilled Fukuda, IOM or CCC and in reality they most consistently met IOM. But the point about...
@dave30th you really must get up to speed on your metaphors. We did it in year 5, along with the siege of Pondicherry. You shut the stable door...
Good point.
I have no knowledge of previous work in the field but I would have thought increased responses were equally consistent with patients being more...
Together these findings suggest that effort preference, not fatigue, is the defining motor behavior of this illness. This comment is meaningless....
That goes a good way to explaining why so many recovered.
Actually, I think it is likely that people making conscious decisions just IS neurons making decisions based on their chemical/electrical...
Nor is it what exertion intolerance is intended to mean, to my mind. The EI in SEID I have assumed implied something like 'food intolerance' in...
A barn door is usually a door twelve feet high and twenty feet wide. So a barn door case is a case about which there is no reasonable doubt. I...
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