It is was if Nath is at the stage of knowledge of ME I was in during the first 3 months of getting interested in it - before going to an IiME...
I think we actually know that already. And even if a slight shift in metabolism shows up on several studies it is more likely to be some...
I would just warn that all this stuff is likely to be wrong. Fluid compartment dynamics is something that 90% of medics and physiologists have...
If I remember rightly there is no evidence for any of the patients in the Mudie study actually having EDS. I think it was just that someone had...
I admire your enthusiasm, Murph but I think the answer is no. Having spent a lifetime chasing clues in pathogenesis in chronic disease I know...
Come on @Hutan, the things you mention make no sense in terms of explaining why PWME are unwell. There are people with gross collagen...
GIGO
Most strategies just kill mid-maturation B cells but the bulk of autoantibody is produced by more mature plasma cells some of which live for...
There is an interesting passage in the Byline Times piece: In 2021, 27-year-old Maeve Boothby O’Neill died after she became too unwell to take in...
It is a long story, hidden in the threads, but in brief. I was involved in the hypermobility story early on in 1978 when Rodney Grahame set up a...
There is no doubt that aggregates containing fibrin that stain with ThioT exist - you can see them in the micrographs. The question is whether or...
It looks as if these post-centrifugation aggregates occur in plasma from people whose coagulation systems are already partially activated in vivo....
Not so much problematic as barn door nonsense. Most walls have some cracked bricks. That doesn't mean that cracked bricks do not cause walls to...
Yer, well, some emeritus professors knows their stuff and others don't, seems to me. Fiona needs to learn a little about the real world of science...
Yet one commonly hears of ME patients being told they have gastroparesis. If it really exists in ME and causes severe weight loss why haven't...
Interesting to see that this pain reprocessing therapy (PRT) seems to have been invented by an NIH project:...
Curable looks to be a rather nasty scam, certainly.
This is pure nonsense, propagated by people like Peter Rowe and Rodney Grahame, I'm afraid. Generalised joint hypermobility just means you have...
This is my worry. I am not sure what easy digestibility would have to do with gastroparesis. High roughage foods are generally thought to be good,...
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