Going back to the beginning and TRACCS: I attended a Grand Round this week given by Dr Segal. The case was of fatigue, possibly Addison's which...
I suspect that simply reflects the current fashion for calling everyone with slightly loose joints 'EDS' following the hype generated by people...
This looks inherently unlikely to be a useful finding but if it is it ought to be presented a different way. Adolescent idiopathic scoliosis is...
It seems they are now suggesting that they were stimulating the trigeminal nerve rather than the vagus?
A number of people will be pleased if another LDN trial is set up. I understand there is already on in Canada for Long Covid. There is enough...
Yes of course it is corrupt. And what probity are we talking about. The system allows complete garbage and fraud through and tends to block...
You have to remember that animal models are always manipulated to just that point where any given influence will make a big difference on the...
Yes, most papers now are garbage. This is the problem. The proportion of papers worth citing twenty years later has gone down from about 30% to...
Human neutrophils are incompatible with mouse endothelium because basic lectin adhesion systems use different molecules. Human neutrophils should...
I have no idea whether there is any real biology here but injections of carrageenan produce pretty dreadful local inflammation often with cell...
Messing about with a mouse's neutrophils in this sort of way is probably a bit like giving them a transfusion reaction or a quick dose of septic...
And I do not understand how it can be ethical to subject mice to things like this when it tells us nothing.
I checked out the references. They are mostly a handful of insignificant studies in poor quality journals that don't even say what the authors say...
This is all a nonsense. If you create an animal 'model' that seems to produce the right symptoms by some arbitrary experimental intervention you...
'A journal' is an abstraction attached to some people. So the question is how should some people make a profit. But if they are the same people as...
I am hoping this will snowball. I have sent my most recent paper to a free of charge open access online journal with open peer review. There is no...
MY point is that this is flanneling. 'Systemic dysregulation' can mean anything and one finding might be the opposite of another. What they need...
This is the central claim in the abstract. But it doesn't add up. If it was right 1. LongCovid patients would be frankly acidotic 2. to a degree...
I must have reckoned it was a waste of time!
I had not really picked up on the CLoCK study. The letter raises some very serious issues - notably the one of informed consent.
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