but then again this is from CAR-T BCMA-CD19, the drop of SSA-ro60 (ro52 graph looks very similar) is so slow here too.. . Why? are these LLPC so...
Jonathan Edwards, what do you think about the results from the teclistamab CD3-BCMA bispecific recently published like SLE case report (NEJM paper...
Maria Leandro's talk is the one I'd be most curious about, too. How do I choose between CAR and bispecific?
@Jonathan Edwards, will you go? https://hartleytaylor-registration.co.uk/docs/CARKprog.pdf
Definitely sounds like Sjogrens! I agree that you might be typical MECFS just more work up than the average patient. Most have ANA measured only...
lower IgG correlates with response because less active disease easier to treat?
Sjogrens hypergammaglobulinemia correlates with disease activity, severity and some extraglandular manifestations. It seems to be reported to be...
I thought Sjogren's especially is known for hypergammaglobulinemia. With early Sjogrens, presenting as dysautonomia, the levels of IgG can show...
What's new? One SLE patient who got Cabaletta CD19 for lupus nephritis had a severe, grade 4 neurotoxicity (ICANS). It says she recovered after...
I mentioned allogeneic CAR-T case reports (BRLmed a company who have also BCMA in the pipeline) in scleroderma and myositis. The part I...
not really. Nothing for Sjogrens, nothing for POTS/SFN which should have a separate trial like with Vyvgart, hope someone from BCMA/BAFF only...
and now almost nobody wants rituximab, so easy to get it . Will it take 25 years so nobody wants CAR-T so I can finally access it? :laugh:
and this especially: First case report from China with donor (allogeneic) off the shelf CAR-T cells lower chemo dose used her disease activity...
This one is also interesting : A woman successfully became pregnant and gave birth to a daughter after CAR-T treatment for SLE "Thanks to the...
Pretty sure I found a study years ago where 60-70% of CIDP had SFN too, and that the same drugs are used (found effective?) like IVIG,...
[IMG] BCMA-CD19 bispecific CAR-T therapy in refractory chronic inflammatory demyelinating polyneuropathy hope this means for SFN too CAR T-Cell...
Exploring the clinical and immunopathological association between Long COVID and Sjögren's Disease in mice and humans Sponsored by: Olink...
[IMG]
I guess, he might mean that because I cant really wait and be untreated for 5 years, I should at least see 6 months data, to see I am not getting...
Dual cd19-bcma SLE researcher, from icellgene, told me to ask 6 months data when doing it...to be sure it's a reset...I guess whoever relapsed for...
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