https://www.pnas.org/doi/pdf/10.1073/pnas.2315990121 25 year old patient with Sjogrens / immune-mediated necrotizing myopathy (IMNM) successfully...
Depends on the study, testing method etc. So can't be concluded yet. Thus, open discussion. Same applies for Sjogrens...you'll find study saying...
I think the benefits in my case were from reducing bacterial overgrowth /SIBO in the beginning, 10+ days, and then overkill. I get the same...
Many of us were diagnosed without dryness and/or SSA, with lip biopsy. My lip biopsy showed 1 focus score even before I developed dryness, over 5...
I can barely spit, and recently had my saliva volume measured and they said it's normal. I couldn't believe it. The ref. range for saliva volume...
See the studies below. Also, note, as you mentioned with ME, in Sjogrens research the problem is they do it on some cohort they had recognized,...
I cant exercise, because dysautonomia. And fatigue I had 2005-2019, then got rid of it after IVIG + abx (I guess something metabolic) but at the...
Metabolic Disorders Causing Fatigue in Sjogren’s Syndrome ABSTRACT NUMBER: 2546 Metabolic Disorders Causing Fatigue in Sjogren’s Syndrome...
There are actually 2 case reports in CAR-T BCMA research on NMOSD, 3 out of 13 patients had also Sjogren's (or better say Sjogren's caused their...
CAR-NK CD19 is being tested in China for Sjogrens so hopefully they release case reports early. SLE case reports look good but they released them...
[IMG] From lupusencyclopedia Join us FEB 3 at 5PM EST for an online talk about CAR-T cell therapy in...
As it was mentioned CD19 might not be enough for patients who have their illness run by autoantibodies produced by LLPC, so promising CAR-T is...
They have CAR-T brand in Australia costing $50K.. and I've heard of other places too, in general doesnt have to cost this much. For HSCT many pwMS...
this is bispecific BCMAxCD3 targeting plasma cells, but there is as we mentioned CAR-T targetting BCMA so wont be surprised if used at one point...
They picked young people on purpose because in the lupus mice model CD19 was enough only when early lupus, at later stages more autoantibodies are...
From 2005 -2018 I thought I had MECFS, never heard of POTS or SFN. Then in 2018 I was diagnosed with that, and I figured I have Sjogrens because...
Rituximab doesnt delete CD19 or CD20 positive cells deep enough, the significant % in tissue and lymph nodes stays and this is the most common...
There are autoimmune studies with dual CAR-T that hits also LLPC, some case reports are already published. 18 cases with SLE cCAR-T with...
A likely* legit brand of CAR-T is available outside of a trial, for SLE (and SS or other more severe autoimmune) indications in China, $100,000...
Well, I have my ways ;) I am not a clinician, I am just obsessed with CAR-T for almost 3 years ;) and not sure what data is confidential,...
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