I don't think that is right @Snow Leopard. In my phase I study of rituximab in RA the primary outcome I chose was C-reactive protein because I...
This looks very problematic. To be robust the method has to make sure there is no way attitudes can influence. If bias is possible it will almost...
A primary outcome measure has to reflect reliability as well as directness. If a direct measure is totally unreliable it is not suited to being a...
From the abstract it looks as if the authors do not understand the process of choosing a primary outcome measure. The result looks pretty...
It isn't clear from the abstract whether the initial MRI findings predicted fatigue improvement or that the change in MRI over 6 months correlated...
It is likely that a small proportion of people diagnosed with ME in fact have an autoimmune disease. But equally, people often get given diagnoses...
Not particularly, the pattern of incidence with age is not similar to autoimmune disease in general. Some autoimmune diseases have odd age...
I spoke to an academic haematologist with expertise in clotting today. They had not heard of any of the Pretorius work or the methods being used....
Such things are a thing of the past, I fear. Everyone at the top has lost the plot since the introduction of the 'internal market'. Fortunately...
I think UC has symptoms that sound very like ME, but the key thing about the cycles of symptoms in ME is that they do not seem to relate to any...
This is a distraction, just as Trish says, but I think the metaphor was in use way before 2014. I wonder if it was hijacked by feminism. I have...
To me the use of glass ceiling seems reasonable, if stretched. I think it means limits due to vested interests within an establishment blocking...
If I were of the twittering kind, Which thank the Lord I'm notsir...
I would be surprised, actually. I think these signs are valid if done carefully. It is not a question of activating reflexes so much as simple...
This seems to be put out by a commercial organisation linked to Birmingham City Football Club and British Transport Police. Interesting.
Indeed. The standard teaching in medicine for the last forty odd years has been that the diastolic is the more important for hypertension. In...
My mum has (remarkably) rheumatoid arthritis and my wife, her sister and I have all had two cancers each. Nobody has ME. These things are around...
Yes, this does not look to me to use reliable enough methodology to want to put much weight on it. A decent population based study with very good...
To be really honest those pictures look like a random selection of dirty slides. There does not seem to be much consistency in the bright objects....
But the drug may block an effective response to vaccination for a month or more and also an effective antibody response to new variant.
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