The original idea of targeting B cells in ME was because some patients seemed to get better after having B cells depleted (for cancer). Then a...
It doesn't make a lot of sense and I think it is a pity this sort of stuff is going around social media. Fibrinogen is the normal soluble protein...
The only valid way to do this is on a population based cohort and the only one I know of - at the ME Biobank - found no relation between ME and...
I would be very cautious about using drugs of this sort in the presence of the pandemic. Patients may have unfortunately died because rituximab...
It would but these look quite 'heavy' to me. Platelets include quite a lot of lipid, which is lighter than water. Loose uncondensed fibrin clot...
This is really unhelpful. It may terrify quite a lot of people and it is full of false arguments.
I wonder if the binding of thioflavin T causes amyloid rich micro-aggregates? Patients with a polyclonal anamnestic antibody response after an...
It is a pity we do not have a haematologist here. I have asked for an opinion but it is probably in an in tray. I will try to explain why, with...
I agree. The problem is actually something quite different. It is the need for doctors to understand enough about biochemistry to be able to...
Spontaneous gout is much more common in men, and even more so in Maori men. Old ladies get gout if put on diuretics. I don't quite get what the...
I have asked a haematologist to look at the MS for me. I don't know if Chris has any haematologists to consult. I think we need expert input on...
Then it should be indicated in the paper. Methodology with fluorescence microscopy is so often inadequate. If one wants work to be taken seriously...
I don't think there is anything new about this to be honest. Adequate hydration has been a priority at least ever since I was a medical student....
It is entirely normal. If blood is taken from a small vein that can only provide a limited supply there is always a risk of clot formation on the...
He is trained as a neurologist. His interests in complementary medicine certainly make things complicated. Looking at the UCLH webpage I wonder if...
Not sure how you return something to a healthier state by stopping it working with a block?
If they have found abnormal micro clots in RA then including three cases of RA in the ME series is just incompetent. I looked up Kell. His...
Yes, I think it is basically a reflection of the fact that nowadays people who work on these things have no basic histological training, or indeed...
Saul Berkovitz is a neurologist interested in ME/CFS, working at the Royal National Hospital of Integrated Medicine.
One thing that perhaps worried me most is that the method section of the paper says nothing about blinding. It indicates that samples were viewed...
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