Didn't the TMG minutes stress the importance of this?
It looks like a feasibility study to see if they could do a trial with 26 patients in one arm and 24 in the other. So may be too underpowered to...
The PACE PIs always try to deflect or blame others. So with the protocol changes they said they were approved by the TSC which is independent and...
I think this is where they try to blame action for ME (the patient charity).
Was that in a response for the NICE guidelines. I think he wanted to recommend against disability aids.
I seem to remember that Wessely was claiming that one small study on one aspect of muscle function meant that there couldn't possibly be anything...
Given it was just baseline data I suspect it was. But it could be it exposed something uncomfortable for them.
I get the impression that the necessary analytics was too complex for them.
I've changed it for you
There is an updated version on the first post now along with a link so non-members can access the document or a link to the document can be sent...
The point that Likert made is that if want to measure someones views on A then you may wish to ask them basically the same question multiple times...
Receiver operating characteristics curve. It plots true positive rate (TPR) against the false positive rate (FPR) using various thresholds so...
They are used as summative but I don't think the story is that simple. For example the CFQ has two major components (physical and mental fatigue)...
I think there are other needs for an inquiry. Its not necessarily about PACE but about the standards of governance that the MRC apply to trials...
They didn't but there was someone accusing Goldacre's team of being misleading by including lots of old stuff and pointing to others papers who...
I think someone had done some analysis and the drug companies had cleaned up their act quite well but universities were less likely to follow good...
I've been wondering about this. Data scientists often talk about the need to have subject matter experts who understand the data in order to get...
Its not just the trial as handled by the MRC but also how they handled issues afterwards. They dismissed complaints including the changing of...
Also from that FoI One of the reasons I think it is important is to understand the reasons given for changes that were made. The ones published...
Did we know that? My feeling for a while is that they slipped in the changes to the analysis plan rather than being explicit about them. These...
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