Also from Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Tübingen, Germany recently: Post-COVID-19 fatigue:...
I don't think so. They try slicing and dicing it a number of ways, but always there's too much overlap, even taking into account the likelihood...
As Rvallee noted, a sickness response pretty much always had to, and has to originate in the periphery, because that is where the infections...
I find this explanation so simplistic and all-encompassing as to not be useful. Presumably, I am a genetically susceptible individual, given I...
I think you are right @rvallee. The finding is just about the specific tissue involved, in mice, responding to the flu. I think it probably...
Yes, the treatment approach would depend a lot on whether the sickness response was to an actual infection, or just something stuck in the 'on'...
Discussion So the following can reduce the sickness response: * NSAIDS like ibuprofen and EP3 receptor antagonists * Ptger3 gene knockout *...
Experiment 6 - are neurons in other parts of the body that express Gabra-1 contributing to the sickness response (to flu in mice)? No. The...
Experiments 5 - how are the NP9 neurons affecting disease progression and viral transcript levels? Flu infection produced similar levels of PGE2...
The work described in this paper is impressive. The authors didn't stop there. Experiments 4 - identifying which particular neuron types are...
Experiment 3 - What type of peripheral EP3 receptors are causing sickness responses? So, the location of the EP3 receptors that seemed to be...
Experiment 1 - sickness responses to flu infection in mice They infected mice with a flu virus, with the mice going on to exhibit sickness...
The authors note that, as well as generalised responses, there can be site specific responses, such as nausea and diarrhoea in response to gut...
Harvard, Boston. I think this paper highlights a number of areas that could be usefully studied with respect to ME/CFS. To me, it makes sense...
Just wanted to reiterate that. Note, the data is mostly from high and upper middle income countries. So, it turns out all those BPS proponents...
Hard to know where to place this one, dealing as it does with FND/conversion disorder, but suggesting an autoimmune mechanism for a subgroup....
https://www.frontiersin.org/articles/10.3389/fneur.2023.1137958/full Open access Team from Kagoshima, Japan Objective: Autoimmune autonomic...
Thanks @voner.
Lovely to hear from you, although those cramps and variable heart rate don't sound fun. Given how hard it is to be investigated for this when the...
A number of us have had conversations with him in the past; a number of us have donated to his research program. I could try again I guess, but I...
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