Hannah Davis Lisa McCorkell Julia Moore Vogel Eric Topol The most interesting thing for regular members here, I think, is that this is in 'nature...
Ha, yes.
Sure, I don't think this trial should have been described as a crossover trial in the published paper, it just has a (very short) baseline period....
I agree, I'm not criticising people with ME/CFS who try things. Trying things is an expression of our desire to get better, our 'fighting...
There was a two week baseline period, and 7 to 8 week treatment period. Participants were given the pills every two weeks and they were told that...
That's really disappointing. That's New Zealand's most eminent scientist with any interest in ME/CFS, promoting DNRS; that's people in the...
Arguably, this is actually the benefit of a crossover trial: comparisons between the set of participants that do the placebo first and the set of...
Here are threads for the two studies mentioned above: The use of low-dose naltrexone (LDN) as a novel anti-inflammatory treatment for chronic...
Looking at the individual data for TNF-a a bit closer, I see that there are a variable number of days of baseline results. That could create an...
At first glance, this study seems ok, although of course very small and fairly short. Note that the y-axis of the TNF-a results varies for each...
Only 8 participants A crossover design, with BL (baseline period) and Drug (LDN treatment period). That's good. Here are the results for the...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489802/ Open access Abstract Fibromyalgia (FM) is a complex, multi-symptom condition that...
https://link.springer.com/article/10.1007/s10067-014-2517-2 Open access Abstract Low-dose naltrexone (LDN) has been demonstrated to reduce...
Yeah, post-hoc subsetting is another indication of treatments that don't really work and researchers desperate to find something to report. (Not...
This is an interesting study, demonstrating the power of genetics to predict the clinical impact of a pathogen. Sadly, despite the article...
https://www.frontiersin.org/articles/10.3389/fmicb.2022.1022356/full Pangenomic analysis of Coxiella burnetii unveils new traits in genome...
Gold lockets all round, I say. Hope there's a good budget for the trial though. There's another argument that might be employed to argue against...
From the NIH's MedlinePlus -they suggest that there are three types of muscle atrophy: physiologic (due to disuse); pathologic; and neurogenic....
I note that a recent study of men with Long Covid Myopathy as a cause of fatigue in long-term post-COVID-19 symptoms: Evidence of skeletal muscle...
I've read a bit more, and I have to note that this discussion about the natural experiments created by changes in female hormones over a woman's...
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