I think its interesting. We've talked about ME being caused by faulty signaling mechanisms (either bad signals or receptors not working) so this...
I agree with this. My belief is that the overrode the protocol by getting the stats plan approved (and the stats plan doesn't discuss why changes...
I think some in the Lords had more of an interest in that they are part of that medical community. I think Lord Winston was one. But not sure...
When there was a House of Lords debate on PACE it was clear that several members had been heavily briefed by the PACE team leading to them making...
I think there is another whole area around PACE that needs addressing which is its use to justify a MUS approach. I think there was a slide set...
Recovery was a secondary outcome in the protocol. As I see it the stats plan in May 2010 replaced the protocol in terms of the analysis that was...
I had assumed that the recovery definition was basically dropped from being a secondary outcome when the stats analysis plan was approved as it...
No because too many are doing the same thing.
Nearly all if not all have the fault of using subjective outcomes in open label trials which is compounded as the interventions seek to change...
I think I read about similar approaches for Leukemia a few years ago. But this seemed to be taking blood out and 'training' cells to recognize the...
I've not read this book but I read some of his papers a few years ago and thought they were good. I have a feeling his work was one of the few...
Yes I don't get these scales - sorry the rest of this post is a rant about questionnaire scales in general! I read some stuff on Likert scales...
Nor me but I did wonder about things like looking at computer activity.
I think I would prefer an approach using activity monitoring I assume PEM would show as a dip in activity. But then if that could be coupled with...
It can't be worse than the CFQ can it? I think certainly not suitable for a primary outcome.
I think James Mowbray was on the list and as I understand it he believed ME was a viral infection but I don't really know what was going on then...
I think the difference between 9.9 and 11.1% of GDP is massive in terms of that additional amount of money that helps smooth a system. I think...
If a lifespan is short (I don't know the how long woodpeckers live) then degenerative diseases may not be a problem. Evolutionary adaptations will...
Yes I believe so he had an early copy hence was able to comment on facebook and is thanked for his help in the main document.
Sorry Leonard Jason he posted some comments on facebook. I've edited my message for clarity. [MEDIA]
Separate names with a comma.
