A lot of people in this field, like Dr Scheibenbogen, have looked at adrenergic and muscarinic cholinergic antibodies in parallel. People coming...
The study I remember was from a group in Copenhagen. T4 levels and autoantodies reduced with rituximab. But the focus has been on ophthalmopathy...
As far as I am concerned knowledge and expertise of clinicians that is not based on hard research evidence is worthless. It is as simple as that....
The abstract does not even say which cells the methylation was in. I doubt they checked brain cells.
Mental gymnastics might be regarded as Dualist?
A randomised double blind controlled trial would certainly be possible and you would not need objective end points if blinded. I just think that...
The paper I have seen using that assay looks difficult to interpret. A bioassay of a human antibody using another species has a lot of potential...
Dear @Badpack You make some valid points but there are a couple of things I would add. Pretty much all effective soluble antibody is made by...
I doubt it is worth speculating much about these antibodies. The differences in levels between controls and disease cohorts are not big enough to...
Precisely. It is non sequitur and deliberately so.
I am not sure the new tool is any clearer on general risk of bias. It is actually wrong where the original tool assumed people new how bias works....
I doubt Gary’s post cancer fatigue would have ever got to Knoop or been considered for psychotherapy. Major thoracic surgery leaves people in...
Because there is a new breed of professionals only interested in personal and political gain rather than the right answer. And they are now in...
I think the Wikipedia account is valid. The paper gives what people who do pragmatic trials want to claim they can do - which simply indicates...
A pragmatic trial does not even tell you if it works - that is the definition of a pragmatic trial - it cannot tell you that. Goodness knows what...
Excellent, more sense than I can!!
Yes, I think it is all politics. The BMJ is doing a jolly good job keeping people well by supporting the cost cutting agendas advocate by both...
My impression is that post viral fatigue is quite well documented as a causal relation - bye things like the decay curve for fatigue in the Dubbo...
So maybe they have ME? Or maybe they have prolonged fatigue of another sort that can be triggered by lots of things. The authors here treat the...
I had a look on PubMed and it seems that Lipkin and Hornig have not published their big viral screen. They presented the findings sometime around...
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