Hi @Manuel, Good of you to come on the forum. As you may know, I am a retired professor of immunology with a special interest in B lymphocytes...
I can see John's point but my memory is that the Dean or Vice Chancellor directed David's queries to Paterson in the first place, presumably...
@dave30th, I haven't had to time to look at all the material in detail but it does not look to me as if your questions last time asked for opinion...
I agree with Adam here. There might be a common pathophysiology but since we do not know anything about it that may not help much. Moreover, the...
Except that as far as I know there are no studies comparing impact of advised sleep plans - if only to show that 'sleep hygiene' should be removed...
Sleep is certainly complex but I am not convinced there is any great value in studying changes in different sleep levels in ME as an index of...
I have no problem with exploring activity or exercise outside of the theory-laden context of GET.
My guess would be that this sort of problem could be reasonably easily dealt with either by souping up the analysis software or back-checking with...
I don't think there is necessarily any need to analyse sleep phases using EEG etc. Recent work seems to suggest that the traditional sleep levels...
An interesting guideline. It reinforces my impression that NICE is producing to sorts of guidelines. One lot is for things often treated with...
If there is I am not aware of anything formalised. It is just that professionals recognise the problems that occur if mobility is not maintained...
Yes, my memory is a bit vague now but one referee required the removal of two crucial paragraphs about problems with blinding. I did not remove them.
Just that they seemed to deserve priority. `The idea would be equally applicable to moderate or ,mild I guess.
I agree that attempts to mitigate problems need to be acknowledged. But if one wants to give benefit of doubt in relation to a trial of this sort...
Well we are already getting patient input. The next stage ought to be to get representative patient input from a community based cohort of...
The main target I see as objective evidence of reduced disability. And by disability I mean not being able to live a fulfilling life so it can...
It would be a good start.
I agree and have given this opinion to NICE. There are ethical problems here that were never addressed initially and remain to my mind insuperable...
Yes, it is dispiriting to see such dumbed-down fluff that completely misses the point pretty much every time. If this is advocacy, who needs enemies?
I am not sure which way you are arguing. If you are not intervening with help you cannot test for a pattern of effect. You can get a pattern of...
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