To the connection to ME/CFS I need to do a bit more reading on that. But from brief look that I could do, I like the itaconate hypothesis a lot....
@V.R.T. No I'm saying the exact opposite. Itaconate boosts Type I IFN production in activated macrophages as we showed both in vitro and in vivo....
@Mij Thank you for highliting our work. If you have questions feel free to ask.
Good, I was worried it's some form of autotranslation. I wouldn't like that. Thank you for the kind touch.
Thank you! Is it just me or is it really written in Slovak?
The same applies to the inhibition of cGAS/STING pathway. It is not itaconate, but derivatives that were shown to modify STING and inhibit it's...
Hi I'm Tom, lead author of the itaconate Prdx5 story. I would suggest Caution with relation of itaconate and inhibition of type I interferon (IFNa...
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