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  1. Wanted! Alive
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    Peptidoglycan of Borrelia burgdorferi can persist in discrete tissues and cause systemic responses consistent with chronic illness, McClune et al,2025

    In StatNews: https://www.statnews.com/2025/04/23/lyme-disease-clues-to-chronic-form-treatment-antibiotics/
    Post by: Wanted! Alive, Apr 24, 2025 at 7:14 AM in forum: 'Conditions related to ME/CFS' news and research
  2. Wanted! Alive
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    Costochondritis and chest and rib pain

    In the months following ME/CFS onset, I developed a pain at the junction between the sternum and rib, not a constant ache but pain when pressed...
    Post by: Wanted! Alive, Jan 16, 2025 in forum: Pain and Inflammation
  3. Wanted! Alive
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    Trial Report Muscular metabolic plasticity in 3D in vitro models against systemic stress factors in ME/CFS and long COVID-19, 2024, Mughal

    Wow! This seems significant to me, exhibiting the effects of patient serum on muscle tissue just in a matter of days. Thanks for posting @Dolphin...
    Post by: Wanted! Alive, Oct 9, 2024 in forum: ME/CFS research
  4. Wanted! Alive
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    A 2-hydroxybutyrate-mediated feedback loop regulates muscular fatigue 2024 Wadsworth et al

    Here is the metabolic pathway for the production of 2HB: a byproduct of (excess) 2ketobutyrate (2KB) mediated by lactate dehydrogenase (LDH), the...
    Post by: Wanted! Alive, Sep 5, 2024 in forum: Other health news and research
  5. Wanted! Alive
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    A 2-hydroxybutyrate-mediated feedback loop regulates muscular fatigue 2024 Wadsworth et al

    Thanks for posting @Andy. This possibly deserves some discussion as to what goes wrong between what is a normal muscle recovery post exercise and...
    Post by: Wanted! Alive, Sep 4, 2024 in forum: Other health news and research
  6. Wanted! Alive
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    Exhaustion in ME/CFS, what is it and what causes it - discussion thread

    I think this gets back to the whole point of this thread and power output is a critical measure of that. When we think back to our healthy selves,...
    Post by: Wanted! Alive, Aug 8, 2024 in forum: Post-Exertional malaise and fatigue
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