Not proposing this as a strong hypothesis, but my ME provided evidence implying that my brain cells were overproducing quinolinic acid during my...
Has anyone ruled out neurological effects? Maybe something in brain or nerve function affects muscle function. Could it be some effect of immune...
It doesn't need to be rare, expensive, risky drugs. Two of my most effective treatments (cumin and iodine) were already in my kitchen. They...
I never noticed PEM from accumulated exertion. I always considered it to be triggered by specific actions (unaccustomed strain on muscles).
I'm optimistic about finding a treatment or cure, because I had temporary full remissions from three unrelated molecules: cuminaldehyde,...
Disorders that cause complete shutdown of a function don't mean that there can't be less severe disorders. My ME has responded to changes in...
However, the type of activity still matters, since the response to dosage varies with the activity. For me, less than a minute of window washing...
When I saw the title, I assumed a biological diagnostic test, meaning biomarker. That would be useful. Imagine if they tested the "chronic...
Maybe that could explain the variations in ME symptoms. If ME does affect mitochondrial activity, it might not affect all these diverse...
That's what I'm basing it on too. Abrupt temporary remissions are rare, but not extremely rare. It's always possible that rare cases represent a...
Some of the possible theories of immune memory causing ME fail my "Does this fit experiences of abrupt switching from full ME to full non-ME and...
An anecdotal report of "I think maybe it's kind of helping" isn't all that exciting. I was a bit disappointed by the method, because I was hoping...
Useful type of research. We need that sort of detail to figure out abnormalities. I wonder what percentage of papers citing this one will be...
If somehow you did manage to sleep, even a full 24 hrs, when you woke up your body would still be sending signals that you should go to bed....
People with better cognitive function probably have better oral hygiene practices, maybe more varied diet, and other such factors. People with...
"Humanized" mice. I'm picturing mice wearing clothes and using social media. I do wonder how well modified mice actually represent human...
It sounds like an interesting approach. I think ME alters neural function individualistically, so averaging out large numbers of responses would...
Just a guess that they could find similar improvements if they changed the therapy to music, aromas, having a pet chicken, etc, meaning it's the...
Those are examples in which the abnormal proteins persist and/or accumulate. Couldn't there be diseases where the abnormal protein is transient?...
If she doesn't realize the difference between ME and chronic fatigue, the study is kind of pointless.
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