Okay, I have answers! Yay. 1) Aspects of fibroblast cell culture that I raised appear to be handled sensibly, carefully, thoroughly and...
Paul Hwang sent me a couple of lovely responses, seems like a really nice guy. I didn't get the full picture because he's out of the office and my...
@chillier thanks for asking for detail and holding my statements accountable. Should actually happen more. Density (contact inhibition): I don't...
I see that we may be having similar friendly conversations away from s4me :D very exciting To add my own experience: we did not see an effect of...
I think of it as: DNA is the blueprint, mRNA is a photocopy of the blueprint sent to the factory floor, protein is what the photocopy tells the...
I do, and I agree and am currently playing with it, but the information is sadly incomplete because we don't have access to the patient records of...
Interesting. The lipidomics I presented at IACFSME 2023 showed broadly elevated levels of lipids in lymphoblastoid cell lines generated from pwME.
I really hope this is an English issue more than somebody walking in and just defining the disease into their existing research box.
The bottom line with prospective markers is that nothing has been properly revisited and validated in publication since the wave of modern...
You don't need to qualify your questions before asking :). Thanks for engaging in such a great way with your thoughts and questions. There are a...
I want to look at muscle but it's just been so practically challenging. Getting enough material to do the extent of in-depth experiments that I do...
Thanks for the link to relevant discussion. I went down the rabbit hole from your link, and saw some s4me chatter about the unlikelihood that a...
Thank you for the clarification @Jonathan Edwards, I think I misconstrued one or two elements of your post. I agree with your frustrations...
Not mutually exclusive. Also, yes, if a biological feature being used as a diagnostic is one that's related to the underlying causal mechanism,...
Whole blood mito material will be affected by muscle damage due to physical activity, was physical activity prior to sampling, per individual,...
Sorry that i saw this so late, I don't keep good track of my s4me notifications and rarely have time for a thorough browse. My recollection was...
Very compelling ideas. I really can't wait to meet her in a week or so at IACFSME. I think she's at the forefront of the field right now. Very...
Yep, I will be. It's not final and needs a lot more analysis, and is only a small update on a small branch of the projects I'm working on, but I...
I think I probably phrased things poorly in a hurry to post that between tasks in the lab. You're of course correct. What I mean to say is that I...
"Autoimmunity is considered as a key causal factor for diseases like ME/CFS." Is it? I didn't know that we figured out what's causing the disease...
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