The “something in the blood” is not a virus I believe. Bhupesh Prusty believes that a virus is still active. Whereas the Liver injury hypothesis...
Interesting work in the sense that they use a novel method to analyse cortisol patterns. To be honest i've never heard the algorithm they used and...
Bile acid metabolism disruption has been identified through the methods i use since 2015 so i had time to look at the specific topic for quite...
@Hutan Thank you for the analysis you provided. I was not able to read very closely the paper but i wanted to ask regarding the following...
I wonder whether it is possible that many metabolites have a temporal aspect which is not taken into consideration. So there may be metabolites...
We do not know what is going on , that's for sure. I have not stated that brain injury is the primary cause of ME but i am suggesting hypotheses...
I read references regarding this possibility and yes, it seems that when such an event takes place, there are major disturbances to the hormonal...
It seems that the role of Bile acids is not only for fat absorption but they play a very important role on the regulation of immunity. I hope...
This i believe is one of the most relevant parts to ME (hypothesis) :
cc @Perrier I had a discussion with Jen Brea on Twitter regarding Traumatic Brain Injury (TBI) and ME. TBI was something i never looked at but i...
The problem is that apart from the level of bile acids, we have to look at the composition of them. Both Naviaux and Hanson found issues in the...
Given the paper found by @Andy, i went through my emails and found the e-mail i sent to Derya Unutmaz regarding Bile Acids dysregulation. Derya...
I agree with @Michiel Tack and @Snow Leopard and @Ravn It is very likely that HRV is a non-specific ME marker but nevertheless it can help us to...
Speaking for myself, It was very interesting to experience how HRV would rise by doing simple things such as slow breathing for a couple of...
cc @wigglethemouse @Perrier From the paper @Andy linked above : I wonder if this is all connected : Bile acids dysregulation -> NLRP3...
cc @Perrier This is spot on to what we should be looking at. Looking only to Gut microbiota and not Bile acids is a huge mistake IMHO. Recall...
I did not want to suggest that Derya found CXCR3 to be expressed, i do not know if they looked at this particular marker. I just wanted to show...
I also wanted to post this here apart from Phoenix Rising. I was in contact with Derya on April 2018. He is aware of the "Liver Injury" hypothesis...
Some more details : The ROC curve is typically used in Machine Learning to assess the worth of a machine learning classifier. The diagonal dashed...
I wanted to ask the members of the forum about having translucent teeth. There appears to be a similar thread from @Alvin about teeth problems but...
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