Thanks, Simon. Really useful and clear summary, as always. This seems like something of a paradox. But this type of paradox can lead to exactly...
TG: “oo what have I missed?” A very large ME/CFS elephant in your front room and a steaming pile of BPS dung that it has been shitting on the...
In a way I see this as a positive. My biggest concern on initial viewing was that the results looked too good to be true. Understanding that the...
It wasn’t me that Hilda referred to in her blog, it was the late great Robert Courtney (aka Bob) who wrote to Tovey and, along with Tom, was...
Ha! Careful, man. The come-down can be pretty heavy so I’m not drawing too deep – just enough to keep me going until the next hit. This reminds...
I had no idea that your expertise extended to jeans, Jo. Will you be my phone a friend if I get on Who Wants to be a Millionaire? I’m thinking...
I second that. Sincere thanks @Dx Revision Watch.
The apparently normal baseline urine metabolite data makes me* think that an abnormality with the process of excreting the metabolites may be a...
Good to see that this is considered in the paper as you quote above. Is it possible that excretion of metabolites could be affected by...
@Jonathan Edwards Is this something that’s been discussed in the DHSC research group that Javid initiated? Is there a thread on that group...
My bold: I just hope that somebody at least tries to replicate it. Not infrequently these pilot studies seem to turn up interesting results that...
Tweet from Maureen Hanson: “Despite a small sample size, our pilot study on the urine metabolome turned out to be much more interesting than we...
The word Evidence in Evidence based-medicine seems to be used in the same way that Democratic is used in countries with Democratic in their...
ME Research UK was set up by a an ME patient who was a vascular scientist (Vance Spence). From memory they have funded various studies looking at...
Uninformed question, but I’m just wondering if there is enough data on genes which are associated with NO production/release to make it worth...
If discussing non-ME politics wasn’t against the rules I might have drawn an analogy with certain politicians (and one in particular) who have...
I’ve not managed to follow this thread closely for a while so apologies if I’m repeating. @Andy is there another press release planned to try to...
Also: Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies (2022):...
See also: Peripheral endothelial dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome, 2020, Scherbakov et al:...
I only skimmed it but this was what concerned me. Overstating what is known is unhelpful in so many ways. In particular, it undermines the...
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