Thanks. Maybe I am using it wrong but it came up with nothing when I entered the rsID. Is it true that certain SNPs are only checked for in newer...
@ScottTriGuy You got a SNP number for that? I would like to check also.
Any ideas how long the process will take until I can get the test privately or go to my GP and ask for it? I should imagine a very long time, no?
Somebody over on PR did a very low / zero tryp diet and if I remember correctly didn't notice any improvements however I think he said he did...
Does anyone know if eating sugar causes liver to release more glucose within 2 mins of eating? Either way for me, I get significantly worse after...
True but what I was thinking was if a cell is struggling to produce enough energy through mito would it not import more pyruvate such that this...
@deleder2k I tried to get alcohol to work for me. If PDH is indeed inhibited in ME then you could supply sufficient acetyl CoA through ethanol....
@Jonathan Edwards the diagram is from wikipedia. If the H+ is coming from the cytosol and combining with pyruvate to form lactate then that H+ is...
Two things that I don't understand. First is the diagram shows a H from NADH joining pyruvate then a H+ leaving pyruvate. There is a change in...
@Jonathan Edwards Not sure. I thought that excess NADH was used up by pyruvate to generate lactic acid. Pyruvate no excess hydrogens -> lactate 2...
Not sure what the evidence is but the lactic acid build up feeling the some get could be causing pH changes in the cell, right? pyruvic acid would...
@boolybooly I have read previously about the TH2 shift from MCT however I have noticed no such effects and am generally not alergic to things, it...
@boolybooly I too have lactic acid build up unrelated to deconditioning that is worse with carbs. I also had that breathless sensation when it was...
Interesting. It appears some people had success with DCA over on PR but it did nothing for me.
@Andy I remember reading somewhere that 2 pyruvate are required to enter the mito and operate the PDC. One gets turned into Acetyl-CoA and in turn...
Yeah according to wikipedia it increased adrenaline. It makes you tired because it also is an antihistamine.
FWIW Mirtazapine helped me POTS symptoms significantly when they were real bad. The day after I started taking it I noticed I could stand longer....
Whilst it is better than nothing it is still pretty meaningless. Nobody is going back and listening to old episodes, they should have done the...
It appears the Guardian is more interested in being seen as pro-science than actually being pro science. Garbage newspaper.
@ukxmrv With that description of silly season, it is silly season year round and has been for some time.
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