The efgartigimod trial had a symptom questionnaire as an outcome (compass?) that many POTS patients say is not a good measurement for the...
Does Daratumumab also affect T cells etc? Or if that has a positive effect can we narrow down what is potentially being affected?
If IgG only lasts 100 days, how would lowering it cause the sort of long term remissions that were reported in the cyclo trial? Hypothetically...
Efgartigimod also lowers IgG I believe...
I am really interested in whether the efgartigimod trials failed because they used a very restrictive POTS measurement. A lot of participants...
If the science does not 'come through' for us, what do we have really? Mild people might have a positive response to mestinon or ldn and go back...
This conference should have a keynote speech on what went on with PACE. Perhaps in five or ten years conferences like this will do.
As someone who Is diagnosed with generalized anxiety disorder, I can see both sides of this argument. I was diagnosed by a gp age 19 because I...
Oh and very impressed that the samples were from severe patients, very sensible!
Also I just want to say that to my layman's eye this 3d muscle stuff looks very impressive. If as @wigglethemouse quotes Morten here, the follow...
To clarify I was referring to this post, in which Murph had been in contact with the author by email
Had this feeling last night and this morning, first time in a couple months. Absolutely unbearable.
I think a lot of this is down to funding. If there were similar funding to other conditions, people would be much less opposed to semi random drug...
I think the difference is in our perception of how likely basic science is to produce a result. Surely we feel that good science done methodically...
If your theory is correct, what kind of treatments would we be looking at?
From reading a lot of the patient stories and hearing what the researchers say it seems like some people benefit a lot but most don't respond or...
Posted at the same time! I caught the 3d muscle seminar, inadequate summary above.
Watched the 3D muscle presentation. To my layman's ear it all sounded absolutely facinating. They seemed to have found loads of significant...
The only genetics paper i remember is the SIPS one from a very small number of patients. No capacity to hunt it down now apologies.
That seems like a worthwhile project in terms of replication. Beyond frustrating that funding has been pulled. I hope that the government sees...
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