The 5 items on DSQ-PEM all concerns fatigue. If fatigue is going to be the measure, then the time spend lying down would be simpler to measure and...
Any idea where I can find (HighY vs LowY) after X? I'm presuming Y is ATG13 and X is Rapamycin.
I went through previous threads on ATG13 to see if I missed something. All I could find was pretty much what's on this thread: high ATG13 in...
I had to think about this for a sec since all population (ME/CFS) in their trial presumably have highY (high ATG13) to start with. But then, it...
Why not just trial properly for the ME/CFS responses if they are trialing for ME/CFS? We don't know if the intermediate markers are actually...
I don't fully understand the reason for not including the control, but it appears they are trialing primarily for the ATG13 response to Rapamycin,...
The software/hardware analogy refers to function/physiology in case of the brain. A computer needs to be programmed to function, and replacing...
I agree: foisting psychology without reliable data can do huge harm. I'm strictly limiting the possibility of "software" problem to well-defined...
Firmware is basically unmodifiable software written in read-only memory. Hardware never becomes software. Memory is a hardware, but it is not...
Because of the possibility that neuronal circuitry/connections can be trained/retrained? Again, there are instances of these. I only can speak...
That's probably true insofar as the brain circuitry is made of neurons.
I wouldn't advise it. 30 sec is plenty of duration to trigger PEM depending on what you do. Squatting down a couple of times used to give me PEM...
I'm referring to so called "software" problem. There are instances of maladaptive automatic motor responses to sensory input. That's not too...
I don't follow FND, so I'll have to take your word if you are saying there hasn't been any RCT. Googling seems to indicate otherwise, however (The...
I asked AI too: "The prognosis for organic vision loss depends entirely on the underlying cause, but generally, if left untreated, most cases of...
You said the eye muscle contraction was a structural change. I said that the muscle action is happening without physical intervention or my...
How would a vision loss improve over time?
He's a pretty good, Stanford-educated one. Why ad hominem instead of addressing the point? Xi = C + Yi => delta = Y.
I wouldn't limit myself to the agents recommended for ME/CFS either. I started taking Sudafed to relieve the head pressure that comes with my PEM....
My 2 cents. There is too big a gap between "mild", defined as being able to hold full time job but not much else, and "moderate" defined as being...
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