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  1. leokitten
    Post

    An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients Missailidis et al. 2019

    Regulation of Immune Responses by mTOR Abstract mTOR is an evolutionarily conserved serine/threonine kinase that plays a central role in...
    Post by: leokitten, Feb 28, 2020 in forum: ME/CFS research
  2. leokitten
    Post

    An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients Missailidis et al. 2019

    I also just thought of a potential connection to these research results and why rituximab works in an ME subgroup. mTOR activity also regulates...
    Post by: leokitten, Feb 28, 2020 in forum: ME/CFS research
  3. leokitten
    Post

    An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients Missailidis et al. 2019

    mTOR isn’t a backup energy system. It’s one of the most important proteins at the center of the mammalian cell stress sensing pathways. Remember...
    Post by: leokitten, Feb 27, 2020 in forum: ME/CFS research
  4. leokitten
    Post

    An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients Missailidis et al. 2019

    It could be due to the reasons laid out in this paper. Ex vivo lymphocytes are generally metabolically quiescent and respire at such a low rate...
    Post by: leokitten, Feb 26, 2020 in forum: ME/CFS research
  5. leokitten
    Post

    An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients Missailidis et al. 2019

    What I also like about the results they found is the plausible connection between ATP synthase inefficiency -> upregulation of mTORC1 to make up...
    Post by: leokitten, Feb 25, 2020 in forum: ME/CFS research
  6. leokitten
    Post

    An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients Missailidis et al. 2019

    Well put. Or it’s changing their programming maybe not permanently but for a long enough time.
    Post by: leokitten, Feb 25, 2020 in forum: ME/CFS research
  7. leokitten
    Post

    An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients Missailidis et al. 2019

    Two very intriguing papers by this new lab entering ME/CFS research (Fisher). It shows that the small ME/CFS research community desperately needs...
    Post by: leokitten, Feb 25, 2020 in forum: ME/CFS research
  8. leokitten
    Post

    Havana Syndrome: U.S. and Canadian diplomats targeted with possible weapon causing brain injury and neurological symptoms

    Thread already exists on this topic...
    Post by: leokitten, Jul 7, 2019 in forum: Other health news and research
  9. leokitten
    Post

    Tinnitus Poll : Making a distinction of subtypes

    I almost never had any tinnitus before getting ME. Now after I would get loud and short bursts of tinnitus in one ear or both ears during or...
    Post by: leokitten, Jun 29, 2019 in forum: Neurological/cognitive/vision
  10. leokitten
    Thread

    Metro UK: “You Don’t Look Sick” Weekly Series

    https://metro.co.uk/tag/you-dont-look-sick/ A weekly series published every Sunday telling the stories of people with invisible illness and...
    Thread by: leokitten, Apr 7, 2019, 11 replies, in forum: General ME/CFS news
  11. leokitten
    Post

    NIH: Accelerating Research on ME/CFS meeting, 4th and 5th April 2019

    For those who were concerned about empty seats at the conference... Masur Auditorium has 488 seats. Before they removed the participants list...
    Post by: leokitten, Apr 6, 2019 in forum: General ME/CFS news
  12. leokitten
    Post

    NIH: Accelerating Research on ME/CFS meeting, 4th and 5th April 2019

    The flavonoid Dr Levine mentioned was NeuroProtek
    Post by: leokitten, Apr 5, 2019 in forum: General ME/CFS news
  13. leokitten
    Post

    NIH: Accelerating Research on ME/CFS meeting, 4th and 5th April 2019

    Hi all - I've had pretty major PEM starting yesterday evening, it was a long and tough day. Had major sleep disturbance as I often do the night...
    Post by: leokitten, Apr 5, 2019 in forum: General ME/CFS news
  14. leokitten
    Post

    NIH: Accelerating Research on ME/CFS meeting, 4th and 5th April 2019

    Regarding the immunometabolism talk it was interesting... have there been any high quality studies examining metabolism in ME/CFS in non-immune...
    Post by: leokitten, Apr 4, 2019 in forum: General ME/CFS news
  15. leokitten
    Post

    NIH: Accelerating Research on ME/CFS meeting, 4th and 5th April 2019

    I took a picture of the auditorium but when tried to upload it’s too big and don’t know how to resize just from my phone so will upload tonight sorry
    Post by: leokitten, Apr 4, 2019 in forum: General ME/CFS news
  16. leokitten
    Post

    NIH: Accelerating Research on ME/CFS meeting, 4th and 5th April 2019

    I think though his HLA genetic risk factors work is very interesting
    Post by: leokitten, Apr 4, 2019 in forum: General ME/CFS news
  17. leokitten
    Post

    NIH: Accelerating Research on ME/CFS meeting, 4th and 5th April 2019

    Hard to tell you accurately by scanning the crowd.
    Post by: leokitten, Apr 4, 2019 in forum: General ME/CFS news
  18. leokitten
    Post

    NIH: Accelerating Research on ME/CFS meeting, 4th and 5th April 2019

    I personally think there was really nothing there in the Montoya cytokine results... all moderate patients were no different than controls. I’m...
    Post by: leokitten, Apr 4, 2019 in forum: General ME/CFS news
  19. leokitten
    Post

    NIH: Accelerating Research on ME/CFS meeting, 4th and 5th April 2019

    Hi all from the conference! Not sure if mentioned in thread but auditorium is pretty full, I’m impressed with the turnout as this is a very large...
    Post by: leokitten, Apr 4, 2019 in forum: General ME/CFS news
  20. leokitten
    Post

    A SWINDON MP has welcomed the move to ban adverts claiming to cure autism. Mentions ME/CFS.

    Regarding IQ yes I agree, it can be a convoluted measure. What I was trying to convey is that a significant percentage of people with autism have...
    Post by: leokitten, Mar 28, 2019 in forum: General ME/CFS news
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