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  1. leokitten
    Post

    Kynurenine metabolites and ratios differ between Chronic Fatigue Syndrome, Fibromyalgia, and healthy controls, 2021, Groven et al

    Yep... exactly what I thought after reading it thank you!
    Post by: leokitten, Jun 6, 2021 in forum: ME/CFS research
  2. leokitten
    Post

    How effective are common medications: ... meta-analyses of major drugs, 2015, Leucht et al

    Very true, but I just don’t think we are going to overhaul the clinical trial and regulatory approval system on top of trying to find a treatment...
    Post by: leokitten, Jun 3, 2021 in forum: Other health news and research
  3. leokitten
    Post

    How effective are common medications: ... meta-analyses of major drugs, 2015, Leucht et al

    Or statins for preventing major cardiovascular events. It could be that ok the drugs aren’t bad it’s that people taking them think ok now I don’t...
    Post by: leokitten, Jun 3, 2021 in forum: Other health news and research
  4. leokitten
    Thread

    How effective are common medications: ... meta-analyses of major drugs, 2015, Leucht et al

    A meta-analysis review worth reading, giving pause to how truly (in)effective many common FDA approved are compared to placebo. How effective are...
    Thread by: leokitten, Jun 3, 2021, 8 replies, in forum: Other health news and research
  5. leokitten
    Post

    Aripiprazole - Abilify

    Isn’t it true for most (if not close to all) FDA approved drugs, that during their successful phase III trials that were key to their regulatory...
    Post by: leokitten, Jun 3, 2021 in forum: Drug and supplement treatments
  6. leokitten
    Post

    Aripiprazole - Abilify

    If you went up in dosage I would expect it to cause sleep difficulties again until it normalizes?
    Post by: leokitten, Jun 2, 2021 in forum: Drug and supplement treatments
  7. leokitten
    Post

    Aripiprazole - Abilify

    Going back to Abilify and potential pathphysiological mechantistic clues… Here’s a question, let suppose that the theory that the core pathology...
    Post by: leokitten, May 27, 2021 in forum: Drug and supplement treatments
  8. leokitten
    Post

    Aripiprazole - Abilify

    I've been trying to tell Janet Dafoe and Ron via PR about brilaroxazine. To me so far in phase 1 and 2 clinical trials and other published...
    Post by: leokitten, May 23, 2021 in forum: Drug and supplement treatments
  9. leokitten
    Post

    Aripiprazole - Abilify

    Im not on the FBK group but if it’s anything like the Reddit CFS group of which I’ve read I believe all the posts regarding Abilify, it’s really...
    Post by: leokitten, May 23, 2021 in forum: Drug and supplement treatments
  10. leokitten
    Post

    Aripiprazole - Abilify

    In fact, at the very low dosages pwME are taking there’s significant experimental evidence that Abilify not only stabilizes dopamine but boosts...
    Post by: leokitten, May 22, 2021 in forum: Drug and supplement treatments
  11. leokitten
    Post

    Aripiprazole - Abilify

    Did those family members take the ultra low dosage Abilify and get TD from that? Did they have ME and were taking low dose Abilify to treat it? Or...
    Post by: leokitten, May 22, 2021 in forum: Drug and supplement treatments
  12. leokitten
    Post

    Aripiprazole - Abilify

    Yes, exactly, and by A LOT.
    Post by: leokitten, May 22, 2021 in forum: Drug and supplement treatments
  13. leokitten
    Post

    Aripiprazole - Abilify

    I knew that trying to be as detailed as possible would probably get confusing. It’s really hard sometimes to describe clearly how this illness...
    Post by: leokitten, May 22, 2021 in forum: Drug and supplement treatments
  14. leokitten
    Post

    Aripiprazole - Abilify

    One aspect of my ME that Abilify appears to have little effect on is my suspected mast cell activation problems in my gut and lower abdominal skin...
    Post by: leokitten, May 21, 2021 in forum: Drug and supplement treatments
  15. leokitten
    Post

    Aripiprazole - Abilify

    The biggest difference by far I can remember, and this is a huge difference - is with the ketogenic diet after the first couple weeks, where I...
    Post by: leokitten, May 21, 2021 in forum: Drug and supplement treatments
  16. leokitten
    Post

    Aripiprazole - Abilify

    For those who are new to this thread and reading about Abilify for ME thinking, "could ME be a neuropsychiatric disorder?", the answer is no. It's...
    Post by: leokitten, May 21, 2021 in forum: Drug and supplement treatments
  17. leokitten
    Post

    Aripiprazole - Abilify

    This paper has useful pharmacological and kinetic information: RP5063, an atypical antipsychotic drug with a unique pharmacologic profile,...
    Post by: leokitten, May 20, 2021 in forum: Drug and supplement treatments
  18. leokitten
    Post

    Aripiprazole - Abilify

    Brilaroxazine (RP5063) is also being trialed by Reviva for PAH because of its effects on serotonin receptors.
    Post by: leokitten, May 20, 2021 in forum: Drug and supplement treatments
  19. leokitten
    Post

    Aripiprazole - Abilify

    Initial Clinical Experience of RP5063 Following Single Doses in Normal Healthy Volunteers and Multiple Doses in Patients with Stable Schizophrenia...
    Post by: leokitten, May 20, 2021 in forum: Drug and supplement treatments
  20. leokitten
    Post

    Aripiprazole - Abilify

    Here’s the paper on the phase 2 clinical trial results for brilaroxazine. Abilify is also an arm in the trial (powered for sensitivity not...
    Post by: leokitten, May 20, 2021 in forum: Drug and supplement treatments
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