I'll do my best to summarize my working hypothesis briefly. It mostly addresses the question of why some but not all activity triggers PEM, and...
I suspect that there are also overlapping levels of cellular metabolism regulation at both the cellular level and systemic level. For example, we...
Unfortunately I think your speculation is actually just spot on. And I think this is a problem that extends way beyond the pragmatic...
I have seen this, but thank you for bringing it up again. I was hoping there might be something more directly ME/CFS related, though this LC...
Sure, feel free to look through my previous comments on this thread. I've discussed possible answers to those two questions several times, as well...
You are absolutely right that there are many many possible points of "failure" within the multiple overlapping systems that go from glucose...
Additional commentary on the same citation that others have quoted: “Airborne volume of saliva droplets in healthy subjects is 3–5 orders of...
You’ve been speaking with multiple researchers on this thread alone.
None of that changes the fact that it continues to be unethical to encourage people to believe that their illness is the type that is curable by...
Thanks for sharing! This looks interesting, I’m looking forward to reading more about the methods when it comes out. I’m very curious how they...
Excessive thirst can definitely be caused by other issues besides electrolytes, most notably in diabetes because of excess glucose in the...
It’s a possibility, though many signaling molecules of interest may have a very short half-life (on the scale of minutes/hours), which is why I’m...
A non-falsifiable idea of psychological origins of illness, without definitive proof of those psychological origins, is harmful in itself. the...
Yes that’s definitely on my mind as well. I think that’s what would inevitably happen in a signaling cascade. What you would need for a...
Probably would have to be a small sample size anyway to afford to process all those samples.
I’m aware! I promise I’ve done deep dives on much of this for my PhD research—I was just pulling two examples off the top of my head to show that...
My therapy encompassed both. Because I wanted desperately to get better, I really truly tried what you are describing here. I tried to find...
It seems to be an effect that is only present when the gum is actively being chewed, and their formulation continuously releases the trap protein...
Yes exactly. It would add logistical complexity but I think it would be necessary. What I'm thinking is: 1) multiple pre-activity draws to...
I'd definitely start doing measurements during activity for that reason, though there's a distinct possibility that there's a whole cascade that...
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