[IMG] So it seems like they were investigating the hypothesis that post-COVID effects were due to viral damage to the genome because evidence of...
I think that they’re specifically looking for virus-induced DNA damage in cells, like what UV rays do that eventually leads to skin cancer....
I have a potential collaboration worked out where a generous research team might be able to carry out one preliminary experiment for me. Timeline...
I don’t have specific product suggestions but if you find something that works for you in every aspect except screen brightness, you can buy an...
The reagents necessary to use in the lab can get quite pricey depending on what you’re doing. Many grants do offer some level of discretionary...
Well then I hope my results get published someday because they might surprise you!
Not to further derail the thread, but it turns out I did read some of your group's work a few years ago when I was working on synovial...
That’s exactly my hunch, but it’s pure speculation at this point so I hope nobody puts too much faith on it until there’s data to back it up....
I agree with you on the logic here—my thought is that the cocktail of predispositions are what prevent the boot from doing a good enough job. As...
Yes, to clarify, I meant “predisposing conditions” which could be environmental. Though certainly one of the predispositions could be a genetic...
Bone marrow derived macrophage levels typically fluctuate in response to some insult, but there are also tissue resident macrophages (e.g. the...
The relationship between itaconate, interferon beta, and ROS/PRDX5 is what was found in the paper. A prior paper showed that natural itaconate...
If my speculation is correct, it would be because it requires a hefty cocktail of predispositions before the heavy boot becomes inadequate at its...
This gives me a couple hints as to how the malic acid works. Based on my hypothesis, you’re supplementing malate that would normally be...
I decided to carefully test the upper limits of my activity since I knew I’d have extra recovery time coming up if I needed it. I think what I...
If I’m not mistaken, I think the positive feedback loop Phair is proposing is itaconate -> interferon alpha -> itaconate. I know that interferon...
At this point, my sense is that it is both a cell metabolism and an immune signaling problem at the same time. E.g. immune stimuli cause metabolic...
@Yann04 Hutan's original summary of the talk (corrected at point #2): paulendat's correction that prompted Hutan to modify #2 above: Hutan's...
That's what I suspect, since as Hutan noted earlier, people who are treated with interferon for other infections often report very similar...
I see your point here. Though the more I personally experiment with supplements that affect metabolic function, and see their unique effects...
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