Well done on the film!
It depends on the mutation rate, the types of selection factors (prexisting immunity, vaccines, medications, behaviours), and in turn the sheer...
Overall it covers a lot of ground and is fairly easy to read, it was obviously written with input from a patient. I do have concerns about the...
Yes, it is just more pop-psychology.
I was a participant of this study and it is a followup analysis of some of the other data collected (original manuscript from 2019:...
Yes, just because there is a particular pathway activated doesn't mean it is pathological either, it can simply be a residual effect of the acute...
If we actually understood these pathways in depth, then I'd say yes. But we don't.
An infection after tonsil surgery lead to a wound that kept bleeding.
Exactly. For this study to have any sort of construct validity, they have to go beyond questionnaires.
I don't know as I'd have to see more data. There are others such as the COVAX-19 subunit vaccine from Australia (that isn't produced in...
It's not magic, the subunit is made by inserting the genetic sequence into other species eg yeast, moth larvae, plants, or cell culture, using...
Yes, part of the problem is a lot more quality control processes, due to how they are produced. Novavax seems to be having problems with their...
It means the risk for subunit vaccines is very low because very few spike proteins fragments will be presented on the surface of those cells....
It is not merely the presense of the spike protein, but fragments of that protein being presented on major histocompatibility complex or toll-like...
Controlling for exposure rates is the *basis* of a test-negative case control study. If exposure rates are not controlled, the study is not valid.
Agreed. A more specific diagnostic process is needed for high quality epidemiology studies.
The same study calculated *minus* 13% efficacy for two doses of AZ for the 20-24 year old group. (meaning vaccinated people more likely to get the...
Ouch, I just saw the UK news - 633 cases in one day which is more than the total of Omicron cases in the UK study I linked to.
Latest UK Omicron data. Note the very wide confidence intervals, the fact that protection is at it's peak ~2 weeks after a booster and possible...
We don't know. What I think you are asking is whether our existing vaccines (or prior infection) do lower the risk of severe outcomes - the...
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