Strong Inference Certain systematic methods of scientific thinking may produce much more rapid progress than others. John R. Platt Science,...
This one certainly gets mentioned a lot... While I agree with the conclusion "Full recovery from untreated CFS is rare.", a major limitation is...
Given the absence of other excessive inflammation markers in circulation in most patients, I wonder about the other functions C1Q has (non...
Yes, but the claim of "50%" is not actually based on reasonable quality research. It is the severe persistent symptoms (>3 months) that we care...
Plenty of people live highly stressful lives and don't develop LongCovid (example certain prime ministers and presidents). Plenty of people live...
The immunity may be better, but the overall risk profile is worse...
When I say deconditioned, I obviously mean compared to some prior basis. This may seem surprising, but doing a large quantity of activity...
Someone who does 7000 steps per day can still be deconditioned, because fitness is about intensity, not number of steps.
It is because there is substantial overlap between the blood volume of ME/CFS patients and sedentary controls. To the point that reduced blood...
Oh dear!
Don't see any risk of problems? The outcomes aren't what the patient chooses, they are negotiated with the "multidisciplinary team" (see...
I wish they would focus on severity of symptoms and impact on daily life, rather than merely listing number of symptoms.
Which suggests that most symptoms in these patients is not explained by pulmonary dysfunction.
Yes, their theory does involve the HPA axis, even though they don't explicitly mention it in the current manuscript. The Corticotropin-releasing...
Really? I posted in prior threads why I disagree with their proposed hypothesis and why it doesn't match what is already known about the...
Note that despite all the headlines, this study didn't measure LongCovid as they only analysed data for up to 28 days.
It annoys me that they haven't bothered to investigate the obvious - namely there may be other tick-borne infections that are specific to...
Also note, the claims that patients were more sensitive to the hemodynamic effects of the drug is not generalisable, given they are not matched...
"Cure". Claims like this are flat out irresponsible...
So what? Post the ITT data anyway, since this is a pilot trial. It just sounds like excuses for not doing things properly. I don't find any of...
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