I'm happy to answer this but I don't want anyone to think I'm recommending this for them. I've had mild me/cfs for 22 years now and I know my body...
I find this very interesting because of an effect I've noticed when i'm on a diet: high risk but slow-building benefit. if i reduce my food...
I recommend against exercise. But I am also open to this being a situation where the poison is also part of the treatment. Consider electrolytes...
This feels like a gigantic pivot from Scheibenbogen away from autoantibodies. Maybe overdue!? But the hypothesis is far too strong given the...
That's unbalanced enough that despite the label I'm wondering if they've actually remembered to log transform on the x-axis. (A protein can rise...
It may have been Naviaux 2017, Sphingolipid was among the strongest findings there : [ATTACH] This idea also brings Naviaux's thinking to mind,...
A parallel expression is "climate skeptic", and they're usually skeptical of there being a problem at all. So my vote is for a name change. I...
I have never stopped thinking about this study and I keep an eye on any new research on UPR. I recently found this pre-print and contacted the...
I agree with this approach. Worrying about absolute p values isn't as important as ranking things and seeing if those things show up near the top...
Couple of points @forestglip 1. I'm loving the embedded google sheets, that works really well for me. 2. I'm very impressed by your interrogation...
This is an unusual but deeply-researched paper, by leading biologists out of MIT in the US. Their work is beautifully explained by @SNT_gatchaman...
this is by Kathryn Melamed, now of UT Austin. She was publishing on me/cfs before covid, with systrom:...
Me a few years ago, naive: Novel biomarkers, YES! Me now, jaded: novel biomarkers, UGH. Nobody ever follows up some random lab's weird expensive...
IN the long run I don't seem to be able to improve my exercise load, but in the short run, sometimes. I've at times increased how far I can walk,...
Moved post I was looking for a good thread to put in some interesting recent progress I've made on IBS, and this one will have to do. I had been...
An interesting matrix to explore with a survey might be I have POTS symptoms, am alcohol intolerant I have POTS symptoms, am NOT alcohol...
I would like to reiterate my original post: DOMS and PEM are different. DOMS is adaptive. PEM is pathological. DOMS is local. PEM is systemic. One...
Near the beginning of my me/cfs adventure, I was in what was essentially remission. I'd been sick really acutely for about 4 months, then suddenly...
There are a couple of athletic phenomena that could share some similarities with ME/CFS. Over trainign syndrome is one: My understanding of this...
Salubrinal came to our attention via the Hwang study on WASF3. That study showed endoplasmic reticulum stress was causing WASF3 production and the...
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