I've encountered references to matrix metalloproteinaise a few times recently. https://en.wikipedia.org/wiki/MMP9 Its functions relate to the...
SHe replies: Glad to hear from you and thank you for your interest in the work (not a lot of it in this space, as you perhaps already know)....
My read of their other papers suggests the distinction is not that it is 3D printed, but that other researchers are using 2d layers of muscle...
There's a 2023 paper here that talks about the history and process behind "3D muscle models". Muscle-on-a-chip devices: a new era for in vitro...
Is this a PEM model? we need so desperately to have a benchtop model in this disease. Working on people is so slow, expensive and variable. I...
Good to have this hypothesis formalised and published. I'm a little skeptical of how widespread this could be as an etiology of mecfs but perhaps...
Small sample but they do also blend two other cohorts in and look for commonalities. This is not game-changing research or cure-finding research...
I'm sharing this because it's an example of a metabolic issue with a barrier component. And involves STAT singalling, which I know the stanford...
IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis Peng Zhang 1 , Junlai Liu 1 , Allen Lee 1 ,...
I think sit / lie flat is an interesting dichotomy but legs up is a very important intermediate. I once had an office job where I wore a suit and...
I'm always interested in any hypothesis with an adrenergic connection. beta blockers have been very useful for me, as has midodrine, an alpha...
Berlin Cures will reveal the results of the BC007 Phase II trial in November at a Long Covid conference....
Excellent group of test subjects. I hope they have continued to follow up with them and seen how their health goes beyond 60 days. From 1170...
You can see some level of self-selection in my response to the email from Baker institute: > thanks for the email. I'm probably going to hold off...
Here's the PICF. It contains some language that will make some people concerned. And some stuff that looks good. The language some people might...
I contacted them earlier in the year but then backed out of actually doing it as I was in a downward spiral at the time and worried about gettin...
Pleased to hear this stands up because it's one of those things where I wasn't sure if it was folklore. I've heard it repeated a lot but also seen...
So just to clarify what you two are finding: there is a small difference between mecfs and healthy on a 2 day cpet ? Is that the top line?
I'm just hearing about paneth cells and they seem interesting. Here's two papers. First a background primer on how they maintain intestinal...
What was in common between Younger's video above and Cort's write-up is emphasis on the increased volume of research now (and increased number of...
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