If someone want ed to validate how LC was being coded and diagnosed they would need to take a random sample of patients who think they have it -...
That really makes Cochrane a joke as an organization how can they give any sort of positive rating to anything measured by an incoherent set of...
I don't think it matters what the diagnostic criteria were really since the trial gains were likely to be due to reporting bias. I think that...
I'm wondering about the indirectness thing having quickly looked at what they are saying in the guidance...
I think any trial using the CFQ as an outcome should be rated as very low quality. It suggests a lack of competance in those running the trial as...
If I remember correctly PACE used the london criteria (although perhaps a strangely modified version) which has PEM as a requirement. There...
Cochrane could have explored very different ways to approach a review more as an 'open source' type project than a small group of 'experts'...
Lets face it the Cochrane statement in the first place is very poor in terms of patient participation. Keeping patients informed is not patient...
This basically means an improvement on three questions in the SF36 questionnaire. But a problem I have with this as a measure is if you look at...
Short term research contracts is how much of academia runs in the UK.
I think its interestin that she was working at Griffith University in australia until 2016 where I think they have biomedical ME research...
I suspect if you promote a potential treatment to patients where there are none you will get a relatively positive result from many. Hence I was...
It would be interesting to see the request they put in for ethics approval considering that PwME can relapse with exercise - I wonder if they...
No idea but they have £1.36m to do it. https://www.ucl.ac.uk/news/2021/feb/ucl-researchers-lead-ps11m-projects-investigate-long-covid
Look at the co-investigators they include Crawley and Chadler so the research is likely to be very poor. [Added] In addition they are using the...
This looks like an interesting figure. Anyone know how it compares to the Dubbo study in terms of decrease in numbers ill?
There could be causation though people with ME can get alcohol intolerence so maybe the more severe do tend to avoid alcohol (and limit exercise...
It is one of the reasons to stress the need for high quality science and proper evidence rather than individual anecdote. Although I tend to think...
It was a great find. I think that shows the power of the patient community here. Lots of people contribute hugely to finding information,...
Its interesting as they clearly now realize they were on the wrong side (although really there response was one of inaction, refusing to say that...
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