My thoughts exactly.
Autoimmunity does not depend on memory T cells though, only memory B cells. As far s we know the T cells are all normal.
God knows what any of that means.
We did our best with ritual and cycle but didn't have the justification for going more aggressive - and it was not clear how we could do that,...
Well some guys sent a rocket to the moon when I was a kid. This should n't be harder than that.
Piece of cake, isn't it? But seriously, yes, it should not be harder than sending a rocket to the moon.
I am not aware of any immune or metabolic changes in 'FM'. As usual I would be more inclined to read this if they gave some actual data in the...
That is a reasonable concern and certainly our logic for standard autoimmune disease. However, it is conceivable that people accumulate plasma...
For me the key problem is what has the immune system 'learnt' and 'remembers' that makes it keep on producing the wrong response. In RA we hoped...
Do we need to posit an early TNF and IL-6 response? Why not have an interaction that just produces interferons? As far as I know there isn't any...
Yes, the reductions simply show that the drug is doing what it is designed to do.
Bansal seems just to be using autoimmune encephalomyelitis as an example of widespread brain abnormality: How this occurs is unknown but there are...
Sure, I was being as conservative as possible for the sake of the argument. I probably meant to put 'very severe'. If there are 60,000 then it is...
Yes, but I think very early cases are most likely to give a clear signal.
I don't that there are much in the way of other replicated abnormalities in ME/CFS. We know about age of onset and sex ratio etc. but if you want...
My thought is that if DecodeME comes up with genetic links it would be very useful to look at patients presenting under 15 to see if the link was...
These spot assays require technical skill from the researcher, and finesse with it, but there are plenty of people with those. We did some early...
The interesting thing about Campath is that it was given to people with rheumatoid, by friends who were still stuck in the T cell dark ages for...
Trouble is there will always be some IL-3 or IL-49 enthusiast who claims it is 'important' for autoimmunity and inflammation. Once you start...
One specific thing that I think may be putting people of the scent is that peripheral blood mononuclear cell metabolism probably tells us thing...
Separate names with a comma.
