Very much so. Brain itself has very personal matrix ingredients and does not rely on collagen and elastin in the way most tissues do. But meninges...
We have known for a long time that many EDS genotypes are defects in collagen-related genes - i.e. ECM. But the disease of elastin/fibrillin...
My hunch is that the T cells would be hard to find - a bit like the night cleaners on the metro.
The first step would be to look at patterns of adsorbed signalling proteins on matrix fibres using biopsies and immunochemistry. Calibrating...
The figures of 50-80% of people with CFS having Chiari suggest that most of these patients are even less likely to have had Chiari than ME/CFS....
I think Garner and Carson are on solid ground in their critique of 'micro-clots' which aren't even micro-clots, they are precipitates in test...
Thread split from The itaconate shunt hypothesis A wild card theory I have toyed with for some years is that the pathogenic signalling in ME/CFS...
The key thing, Chris @MelbME, is to remember not to try to teach this load of grannies to suck eggs. Or at least, by all means try - I do it all...
Presumably "Retsina" is out of patent after 2500 years.
I believe it's quite common on this website when people read some threads. And violent with it.
So he believes in Psychosomatic Exertion Malaise??
I think someone is overstepping the evidence base and speculating.
Did you manage to access this @ME/CFS Skeptic ?
https://ovidsp-ovid-com.libproxy.ucl.ac.uk/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=ovft&AN=00006114-199301000-00024&PDF=y this may work...
I am absolutely sure that is the case. But slowing the blood won't help the brain metabolically. And if neurone are very active they may want the...
The laboratory cabinet used by Thomas Lewis when discovering the Triple Response due to histamine release. [ATTACH]
That suggests that the tilt table test is of pretty little value as far as I can see.
It would normally but presumably if it hasn't already then there is some reason for not being able to. I don't think one can really make sense of...
It doesn't really make much sense to me I am afraid. I think one would need to specify which cells were staying and which going. New cells come...
For the reasons given in the post above. I am clinically familiar with that situation and it doesn't apply to people with ME/CFS - they do not...
Separate names with a comma.
