@Andy or whoever might know. Is there any particular reason why 20,000-25,000 people was chosen as a target? Is there a power calculation...
Also I asked it for a paper that showed what it was saying, and it gave me a paper which doesn't exist! A paper whose name existed, but not from...
I love the idea of this for asking pointed academic questions but unfortunately a lot of the time it seems to be answering with complete...
@Andy Perhaps you've already thought of this: An idea to recruit more patients that aren't already in ME networks could be to encourage...
Is it possible to get biopsies from lymph nodes? Or is this too invasive and dangerous to do? Do you think there would be much to be gained from...
@Trish @Keela Too These are understandable positions. The way this disease fluctuates makes it almost impossible to attribute cause and effect a...
@Keela Too Thankyou I really appreciate your comprehensive reply, there's lots to think about. I'm in a way surprised about the nastiness of the...
A question in light of my other post about trying tenofovir. Clinicians must follow the Hippocratic oath 'at first, do no harm' , but what's your...
TLDR: considering taking an antiviral taken routinely as PrEP, what do you think about tenofovir for ME, particularly its safety profile? I am...
You can certainly detect significant quantitative differences in expression with this number of samples - it's not like a GWAS as you say. There...
WAVE3 aka WASF3 appears to be predominantly a central nervous system gene. It's expression is mainly found in those tissues according to RNA...
Do you think the female to male sex bias seen in both ME and the majority of autoimmune diseases is suggestive of autoimmune involvement in ME?...
This is great - exactly what i was thinking about. It's quite damning
Thanks, I was trying to find an audiobook version of this yesterday in fact but with no luck. I'll take a look at the text copy instead
I was looking yesterday at a meta review of meta reviews for CBT efficacy in all sorts of conditions, and it found positive evidence of CBT...
Merged thread - article discussed first Abstract here Came across this article in the telegraph reporting CBT and exercise improves fatigue in...
Thank you for the explanations! Do you (Simon, Chris or anyone) know if they reported on rs7337312 ( SLC25A15 ) which looked somewhat promising...
from the body of the paper: "ICP8 was detected in the biopsies of 83.3% (25/30) of Group 1 patients, 73.3% (11/15) of Group 2 patients, and 6.7%...
As an aside I watched the bbc documentary about the novichok poisonings recently and this list of symptoms seemed very familiar! I suppose it's...
The EBV negative MS cases could also either be incorrect MS diagnoses or false negative serology. I don't know what the error rates are for these...
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