Despite the small n=18 sample size and weird issues with categorization of severe ME I really like this paper. I like that by looking at the...
I read the first line and was thinking 'how bad could it be?' I wasn't expecting something that sounds so much like an aphrodisiac.
Another thought about this paper. So far every ME metabolomics paper I've seen doesn't have a disease control. I'm very keen to see that because...
Had a look in hanson urine study and it is lower relative to controls (0.7 of controls) but not significant p~0.3. Armstrong has also done some...
Biology This sounds interesting. It's interesting that all the reductions in membrane lipids they find are unsaturated (containing double bonds...
I'm revisiting some metabolomics papers and thought I'd share some thoughts about this one. I think it's potentially quite interesting. It's got...
The trend if anything looks to me like the fewer sessions you had the better your chances of improvement - for both activity management and GET.
[ATTACH] I just added a red line to this plot to make it easier to visualise (for me at least). If a dot is above the line they improved if it's...
The Bottom Line Keyboard features, in particular left mouse button clicks are able to distinguish between demanding and not demanding cognitive...
Results 3 Breakdown of Left Clicks by individual activity As left clicks appear to be the most informative feature, I have shown the strip...
Results 2 Hypothesis testing results show significant differences in keyboard features but not saccades The results of the hypothesis testing...
Results 1 Data shape Firstly, let's take a look at the shape of the data. Below are histograms showing the distribution of the data for the...
Generally speaking journals as they currently exist are problematic. They force scientists to pay to submit their own papers - funded often from...
All of this is at p=0.05 and unadjusted, so it's possible every one of those genes in that venn diagram is a false positive. To be honest I'm not...
Good of you to take the time to properly look at the data for what is already a fundamentally flawed premise - it's good to give the benefit of...
Here is the heatmap they show of metabolites they see at q < 0.05 in the CSF of their cohort. They're all low in ME. They are arguing generally...
[ATTACH] In this figure they got participants to exert by a grip test for n repeated blocks (denoted b1 to bn), which were repeated until fatigue...
Yes it's mad that PEM as far as I can see is not mentioned once in the entire document. PEM contextualizes all of these decisions and I think if...
"Female healthy participants needed for ME/CFS study in Sheffield! Can you take part in our study as a healthy participant? Or if you're an ME/CFS...
One of the UK Biobank GWAS studies has a nice interactive website (http://geneatlas.roslin.ed.ac.uk/). I thought I'd check if at least any of...
Separate names with a comma.
