No it would be the normal rules for the BBB. BBB normally refers to limited permeability to protein solutes. Cells are called out if chemotactic...
It seems to be this paper, which seems to be a rather obscure study comparing boys and men for 'Mean Power Frequency'. Eur. J Applied Physiol. ....
He opens his tweet (above, quoted by Kalliope) with: "A good overview of the diagnosis and treatment of cardiovascular dysautonomia, e.g. POTS,...
Are you sure that is what it says? The abstract says: Which is something quite different. Or just a pharmacist who works in integrative...
The bottom line is whether you trust a doctor who does not base their practice on reliable evidence. The review article isn't framed in terms of...
If I was cynical (who me?) I would say that is to sell a lot more drug. And even to get patients hooked. No mention of withdrawal state so far. If...
I would have thought that orexin was tied fairly closely in to circadian rhythm if it is involved sleepiness and narcolepsy. In the context of...
It is conceivable that a drug that 'nudges' a circadian rhythm once a night back into giving regular sleep timing could take a month to have full...
What worried me about the Nakatomi images was that they looked like physiological patterns rather than pathological patterns. That made it more...
I agree. And then there is the paradox that there are also long time frame changes like PEM. Which brings us back to maybe both a central neural...
But of course, because the brain is falling apart with cells attacking myelin. And of course they are being looked at post mortem. Glial changes...
I am not sure what glial functions could change in that time other than ion flux - maybe calcium - which I would tend to lump in with neural...
I am afraid this looks very much like re-inventing a wheel that does not actually roll. People seem desperate to have their voices heard even if...
"Can autoimmune diseases be cured? Scientists see hope at last." I saw hope in 2000 when I presented the first results on B cell targeting, and...
We do not have good methods for detecting glial behaviour in living brains. However, for decades we have had excellent histological techniques for...
There is one crucial difference, in that 'OTS' involves a presumed causation, just as 'post-viral fatigue' or 'chronic Lyme' does. 'ME' is purely...
But does it actually make sense? If there are circulating cytokines reaching brain that is an indication that something is wrong somewhere else....
I think it is very difficult. The only thing specific to SJogren's isdryndss of eyes and mouth. You can do a Schirmer test for eyes and a...
And apart from anything else there isn't any increase in circulating cytokines in ME, so the whole thing seems a dead duck.
I am not convinced, to be honest. Yes it is easier to pick up things like demyelination early with MRI but that happened thirty years ago....
Separate names with a comma.
